Leflunomide
Leflunomide (Arava) is the one product here, a disease-modifying antirheumatic drug in 10 mg and 20 mg tablets used to slow joint damage in rheumatoid arthritis.
Medicine containing Leflunomide
Key points
- Leflunomide is a non-biological DMARD that limits the growth of immune cells attacking the joints, slowing disease progression rather than masking pain.
- The active metabolite has a two-week half-life, so side effects may begin or continue even after the last dose.
- Leflunomide carries a boxed warning for birth defects: it must not be taken during pregnancy, and effective birth control is required for two years after stopping.
How does Leflunomide work?
Leflunomide converts in the body to an active metabolite called teriflunomide, which blocks an enzyme the immune system needs to produce new cells. By limiting the growth of activated immune cells, it reduces the inflammation that damages joints in rheumatoid arthritis, a condition managed under Autoimmune Support. The metabolite has a two-week half-life, so leflunomide’s effects, including side effects, may linger for weeks after the last dose.
Further reading
FAQ
What leflunomide products are available?
On Direct Meds, leflunomide comes as Arava. Compare their forms, strengths and packs.
What are other names for leflunomide?
In South Africa it is also sold as Rheumalef and Lunar. Names differ from country to country, so the active ingredient is the surest way to compare products.
How is leflunomide priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Do I need a prescription for leflunomide in South Africa?
No, not online. Direct Meds does not ask for a prescription to order leflunomide. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy leflunomide online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated