Methotrexate Tablets
Rheumatoid Arthritis, Psoriasis
2.5mg · 5mg · 7.5mg · 10mg
Methotrexate tablets for rheumatoid arthritis and psoriasis. It calms the immune system's attack on joints and skin.
From$0.41/ tabletView
Methotrexate
Methotrexate (sold as Rheumatrex) is an antimetabolite used for rheumatoid arthritis, psoriasis and certain cancers. This listing covers Methotrexate Tablets in four strengths, from 2.5 mg to 10 mg.
Medicine containing Methotrexate
Key points
- As an antimetabolite, methotrexate blocks dihydrofolate reductase, stopping cells from building the DNA and RNA they need to divide.
- Methotrexate carries a boxed warning for embryo-fetal toxicity: it can cause birth defects or fetal death and must not be taken during pregnancy for non-cancer conditions.
- The medicine can reduce blood cell production in the bone marrow, raising the risk of serious infections and bleeding.
How does methotrexate work?
Methotrexate blocks an enzyme called dihydrofolate reductase, which cells need to build DNA and RNA. Without those building blocks, fast-dividing cells cannot multiply. In rheumatoid arthritis and psoriasis, this slows the overactive immune cells and skin cells that cause joint swelling and scaly patches. The same mechanism targets rapidly dividing cancer cells in Oncology Support, including those in acute lymphocytic leukaemia.
Further reading
FAQ
In which products can I find methotrexate?
On Direct Meds, methotrexate comes as Methotrexate Tablets. Compare their forms, strengths and packs.
What are the brand names for methotrexate in South Africa?
Methotrexate is also sold under brand names such as Rheumatrex. In South Africa it is also sold as Abitrexate. Names differ from country to country, so the active ingredient is the surest way to compare products.
How is methotrexate priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Can I buy methotrexate over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order methotrexate. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver methotrexate to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated