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Teriflunomide

Teriflunomide, sold as Aubagio, is an immunomodulatory tablet used to treat Relapsing Remitting Multiple Sclerosis in adults and children aged 10 and older. Aubagio 14 mg is the only product listed.

Aubagio

Relapsing Remitting Multiple Sclerosis

14mg

Teriflunomide tablets for relapsing remitting multiple sclerosis. It reduces the overactive immune response that damages nerve fibres in the brain and spinal cord.

From$205.67/ tabletView

Key points

  • Teriflunomide is an immunomodulatory agent that may work by decreasing inflammation and the action of immune cells that can cause nerve damage.
  • It may cause serious or life-threatening liver damage, and the risk rises with other medications that affect the liver or with pre-existing liver disease.
  • Teriflunomide must not be taken during pregnancy or a planned pregnancy, and effective contraception is required before, during, and for up to 2 years after treatment.

How does Teriflunomide work?

In multiple sclerosis, the immune system attacks the myelin sheath, the protective coating around nerve fibres. The molecule teriflunomide is the active metabolite of leflunomide, a medicine used in other autoimmune conditions, and it may interfere with the immune cells that target this coating. It stays in the body for a long time: without a special elimination procedure, it takes an average of 8 months to clear, though this can extend to 2 years.

Further reading