Bactrim
Sulfamethoxazole · Trimethoprim
A sulfamethoxazole and trimethoprim combination for urinary tract infections and pneumocystis pneumonia. Each ingredient blocks a different step in the same pathway.
- Category
- Antibiotics
- Active ingredients
- Sulfamethoxazole · Trimethoprim
- Route
- Oral use
- Form
- Tablet
- Strengths
- 400mg + 80mg · 800mg + 160mg
Bactrim is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Bactrim depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Bactrim details
- Conditions
- Urinary Tract Infections · Pneumocystis Pneumonia · Shigellosis
- Alternative names
- sulfamethoxazole, trimethoprim
- Therapeutic class
- Folate Synthesis Inhibitor Combination
- Pharmacological class
- Sulfonamide Antibacterial
- Known off-label uses
- toxoplasmosis
- Minor side effects
- nausea; vomiting; decreased appetite
- Moderate side effects
- mild rash; pruritus; headache
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Roche
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Warfarin; Methotrexate; Phenytoin
- Age restrictions
- Approved for infants over two months of age, children, and adults.
Contraindications
megaloblastic anaemia due to folate deficiency; severe renal impairment; infants under two months
Serious side effects
agranulocytosis, requires immediate medical attention; Stevens-Johnson syndrome, requires immediate medical attention
Patient summary
A sulfamethoxazole and trimethoprim combination for urinary tract infections and pneumocystis pneumonia. Each ingredient blocks a different step in the same pathway.
Mechanism of action
Cooperatively blocks sequential steps of bacterial tetrahydrofolic acid synthesis, preventing cellular reproduction.
Pregnancy and breastfeeding
Pregnancy: Interferes with folate metabolism. High risk. Avoid during pregnancy. Breastfeeding: Not recommended.
What you will receive
Bactrim names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Sulfamethoxazole / Trimethoprim at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.