Combigan
Brimonidine and timolol eye drops for open-angle glaucoma and high eye pressure. It combines two types of pressure-lowering action in one bottle.
- Category
- Eye Care
- Active ingredients
- Brimonidine · Timolol
- Route
- Ocular use
- Form
- Ophthalmic Solution
- Strengths
- 0.2% + 0.5%
Combigan is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Combigan on your behalf.
- Conditions
- Open-angle Glaucoma · Ocular Hypertension
- Alternative names
- brimonidine, timolol
- Therapeutic class
- Alpha-2 Adrenergic Agonist, Beta-Blocker Combination
- Pharmacological class
- Ophthalmic Antiglaucoma Agent
- Contraindications
- bronchial asthma; sinus bradycardia; severe heart failure
- Minor side effects
- ocular burning; stinging; visual blur
- Moderate side effects
- conjunctival redness; dry eyes; headache
- Dosage forms
- Ophthalmic Solution
- Administration route
- Ocular use
- Originator
- Allergan
- Onset time
- 1 hour
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Systemic Beta-Blockers; Reserpine; Alcohol
- Age restrictions
- Approved for adults and children over two years.
- Pregnancy and breastfeeding
- Pregnancy: Limited human data. Breastfeeding: Expelled in breast milk.
Serious side effects
systemic bradycardia, requires immediate medical attention; severe bronchospasm, requires immediate medical attention
Patient summary
Brimonidine and timolol eye drops for open-angle glaucoma and high eye pressure. It combines two types of pressure-lowering action in one bottle.
Mechanism of action
Combines the aqueous humor synthesis restriction of both agents with the uveoscleral outflow enhancement of brimonidine.
FAQ
Will I receive the original Combigan?
No. Combigan is the original brand, made by Allergan, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredients (brimonidine and timolol) at the same strength. The generic brand and manufacturer depend on available stock.
How much does Combigan cost in South Africa?
The price varies with pack size. Combigan comes in a 0.2% + 0.5% strength, in packs of 2 to 6 bottles, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per bottle.
Payment and prices →What is Combigan used for?
Combigan contains brimonidine and timolol, used for open-angle glaucoma and ocular hypertension.
How quickly does Combigan work?
Brimonidine and timolol usually start to work within 1 hour, and their effect lasts about 12 hours. This varies from person to person.
What are the side effects of Combigan?
The common side effects of brimonidine and timolol are ocular burning, stinging and blurred vision. Less common ones include conjunctival redness, dry eyes and headache. Serious but less common side effects include systemic bradycardia and severe bronchospasm, which need urgent medical attention.
Can I drink alcohol with Combigan?
Alcohol can interact with brimonidine and timolol, so check with a doctor or pharmacist before you drink while taking Combigan.
Which medicines interact with Combigan?
Brimonidine and timolol can interact with systemic beta-Blockers and reserpine. Tell your doctor or pharmacist about every medicine you take before you start taking Combigan.
Is Combigan available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Combigan. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver Combigan to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Combigan names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Brimonidine / Timolol at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.