Combivir
A lamivudine and zidovudine tablet for HIV-1 infection. Both ingredients mimic natural building blocks of viral DNA, causing the chain to stop growing.
- Category
- HIV Management
- Active ingredients
- Lamivudine · Zidovudine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 150mg + 300mg
Combivir is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Combivir depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Combivir details
- Alternative names
- lamivudine, zidovudine
- Therapeutic class
- Dual Nucleoside Reverse Transcriptase Inhibitor (NRTI) Combination
- Pharmacological class
- Antiretroviral Combination
- Minor side effects
- nausea; headache; fatigue
- Moderate side effects
- anaemia; leukopenia; myopathy
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- ViiV Healthcare
- Onset Time
- 2–4 weeks
- Duration
- 12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Ribavirin; Ganciclovir; Methotrexate
- Age restrictions
- Approved for patients weighing over thirty kilograms.
Contraindications
bone marrow suppression; severe renal impairment; hypersensitivity to any component
Serious side effects
lactic acidosis, requires immediate medical attention; severe bone marrow suppression, requires immediate medical attention
Patient summary
A lamivudine and zidovudine tablet for HIV-1 infection. Both ingredients mimic natural building blocks of viral DNA, causing the chain to stop growing.
Mechanism of action
Both agents compete with natural nucleosides to insert into growing viral DNA strands, causing early chain termination.
Pregnancy and breastfeeding
Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Avoid to prevent transmission.
What you will receive
Combivir names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Lamivudine / Zidovudine at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.