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Combivir

Combivir

Lamivudine · Zidovudine

A lamivudine and zidovudine tablet for HIV-1 infection. Both ingredients mimic natural building blocks of viral DNA, causing the chain to stop growing.

All strengths and pack prices
StrengthPackPricePer unit
150mg + 300mg30 tablets$110.00$3.67
150mg + 300mg60 tablets$182.00$3.03
150mg + 300mg90 tablets$252.00$2.80
150mg + 300mg120 tablets$290.00$2.42
150mg + 300mg180 tablets$392.00$2.18
150mg + 300mg270 tablets$538.00$1.99
150mg + 300mg360 tablets$652.00$1.81
Active ingredients
Lamivudine · Zidovudine
Route
Oral use
Form
Tablet
Strengths
150mg + 300mg

Combivir is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Combivir on your behalf.

Alternative names
lamivudine, zidovudine
Therapeutic class
Dual Nucleoside Reverse Transcriptase Inhibitor (NRTI) Combination
Pharmacological class
Antiretroviral Combination
Minor side effects
nausea; headache; fatigue
Moderate side effects
anaemia; leukopenia; myopathy
Dosage forms
Tablet
Administration route
Oral use
Originator
ViiV Healthcare
Onset time
2–4 weeks
Duration
12 hours
Storage instructions
Store below 25°C.
Drug interactions
Ribavirin; Ganciclovir; Methotrexate
Age restrictions
Approved for patients weighing over thirty kilograms.
Contraindications

bone marrow suppression; severe renal impairment; hypersensitivity to any component

Serious side effects

lactic acidosis, requires immediate medical attention; severe bone marrow suppression, requires immediate medical attention

Patient summary

A lamivudine and zidovudine tablet for HIV-1 infection. Both ingredients mimic natural building blocks of viral DNA, causing the chain to stop growing.

Mechanism of action

Both agents compete with natural nucleosides to insert into growing viral DNA strands, causing early chain termination.

Pregnancy and breastfeeding

Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Avoid to prevent transmission.

FAQ

Is the Combivir on Direct Meds a generic?

Yes, you receive a generic. Combivir is the original brand, made by ViiV Healthcare, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredients (lamivudine and zidovudine) at the same strength. The generic brand and manufacturer depend on available stock.

How is Combivir priced?

Combivir comes in a 150mg + 300mg strength, in packs of 30 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

What other names is Combivir sold under?

In South Africa, lamivudine and zidovudine are also sold under brand names such as Lamzid and Duovir.

What is Combivir used for?

Combivir contains lamivudine and zidovudine, used for human immunodeficiency virus 1 (HIV-1) infection.

How long does Combivir take to work?

Lamivudine and zidovudine usually start to work within 2 to 4 weeks. The exact timing differs between people.

Does Combivir have side effects?

Yes. The common side effects of lamivudine and zidovudine are nausea, headache and fatigue. Less common ones include anaemia, leukopenia and myopathy. Serious but less common side effects include lactic acidosis and severe bone marrow suppression, which need urgent medical attention.

Which medicines interact with Combivir?

Lamivudine and zidovudine can interact with ribavirin, ganciclovir and methotrexate. Tell your doctor or pharmacist about every medicine you take before you start taking Combivir.

Do I need a prescription to buy Combivir in South Africa?

No, not online: Direct Meds does not ask for a prescription to order Combivir. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Combivir in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Combivir names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Lamivudine / Zidovudine at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics