Glucovance
Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.
- Category
- Diabetes Management
- Active ingredients
- Metformin · Glibenclamide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5mg + 400mg · 5mg + 500mg
Glucovance is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Glucovance depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Glucovance details
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- metformin, glyburide
- Therapeutic class
- Sulfonylurea, Biguanide Combination
- Pharmacological class
- Antidiabetic Combination
- Contraindications
- severe renal impairment; acute metabolic acidosis; diabetic ketoacidosis
- Minor side effects
- diarrhoea; nausea; headache
- Moderate side effects
- hypoglycaemia; metallic taste; weight gain
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Bristol-Myers Squibb
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Contrast Media; Alcohol; Ciprofloxacin
- Age restrictions
- Approved for adults.
Serious side effects
lactic acidosis, requires immediate medical attention; severe hypoglycaemia, requires immediate medical attention
Patient summary
Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.
Mechanism of action
Glyburide triggers pancreatic insulin output while metformin minimises hepatic glucose synthesis and enhances receptor sensitivity.
Pregnancy and breastfeeding
Pregnancy: Avoid during pregnancy. Glycaemic control with insulin preferred. Breastfeeding: Avoid.
What you will receive
Glucovance names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Metformin / Glibenclamide at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.