Glucovance
Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.
- Category
- Diabetes Management
- Active ingredients
- Metformin · Glibenclamide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5mg + 400mg · 5mg + 500mg
Glucovance is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Glucovance on your behalf.
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- metformin, glyburide
- Therapeutic class
- Sulfonylurea, Biguanide Combination
- Pharmacological class
- Antidiabetic Combination
- Contraindications
- severe renal impairment; acute metabolic acidosis; diabetic ketoacidosis
- Minor side effects
- diarrhoea; nausea; headache
- Moderate side effects
- hypoglycaemia; metallic taste; weight gain
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Bristol-Myers Squibb
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Contrast Media; Alcohol; Ciprofloxacin
- Age restrictions
- Approved for adults.
Serious side effects
lactic acidosis, requires immediate medical attention; severe hypoglycaemia, requires immediate medical attention
Patient summary
Metformin and glibenclamide tablets for type 2 diabetes. The two drugs lower blood sugar by different routes, so one pill does the work of two separate ones.
Mechanism of action
Glyburide triggers pancreatic insulin output while metformin minimises hepatic glucose synthesis and enhances receptor sensitivity.
Pregnancy and breastfeeding
Pregnancy: Avoid during pregnancy. Glycaemic control with insulin preferred. Breastfeeding: Avoid.
Is the Glucovance on Direct Meds a generic?
Yes, you receive a generic. Glucovance is the original brand, made by Bristol-Myers Squibb, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredients (metformin and glibenclamide) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Glucovance cost in South Africa?
It depends on the strength and pack. Glucovance comes in 2.5mg + 400mg and 5mg + 500mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.
Payment and prices →Is Glucovance sold under other names?
Glibenclamide is also known as glyburide, the name used in the United States.
What is Glucovance used for?
Glucovance contains metformin and glibenclamide, used for type 2 diabetes mellitus.
When does Glucovance start working?
Metformin and glibenclamide usually start to work within 1 to 2 hours, and their effect lasts about 12 to 24 hours. This varies from person to person.
What side effects can Glucovance cause?
The common side effects of metformin and glibenclamide are diarrhoea, nausea and headache. Less common ones include hypoglycaemia, metallic taste and weight gain. Serious but less common side effects include lactic acidosis and severe hypoglycaemia, which need urgent medical attention.
Does Glucovance interact with alcohol?
Alcohol can interact with metformin and glibenclamide, so check with a doctor or pharmacist before you drink while taking Glucovance.
What does Glucovance interact with?
Metformin and glibenclamide can interact with contrast media and ciprofloxacin. Tell your doctor or pharmacist about every medicine you take before you start taking Glucovance.
Do I need a prescription to buy Glucovance in South Africa?
No, not online: Direct Meds does not ask for a prescription to order Glucovance. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Glucovance online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Glucovance names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Metformin / Glibenclamide at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.