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Motegrity

Motegrity

Prucalopride

Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.

Active ingredient
Prucalopride
Route
Oral use
Form
Tablet
Strengths
1mg · 2mg

Motegrity is the reference name. You receive a generic with the same active ingredient and strength.

Supply requirements for Motegrity depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.

Motegrity details

Alternative names
prucalopride
Therapeutic class
Selective 5-HT4 Receptor Agonist
Pharmacological class
Prokinetic Agent
Minor side effects
headache; nausea; diarrhoea
Moderate side effects
abdominal pain; decreased appetite; fatigue
Serious side effects
severe depression and suicidal ideation, requires immediate medical attention
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription-only medicine (POM)
Originator
Shire
Onset Time
24–48 hours
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Erythromycin; Ketoconazole
Age restrictions
Approved for adults.
Contraindications

renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders

Patient summary

Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.

Mechanism of action

Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.

Pregnancy and breastfeeding

Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.

What you will receive

Motegrity names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Prucalopride at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics