Motegrity
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 1mg | 30 tablets | $109.00 | $3.63 |
| 1mg | 60 tablets | $158.00 | $2.63 |
| 1mg | 90 tablets | $206.00 | $2.29 |
| 1mg | 100 tablets | $222.00 | $2.22 |
| 1mg | 200 tablets | $385.00 | $1.93 |
| 1mg | 300 tablets | $546.00 | $1.82 |
| 2mg | 30 tablets | $145.00 | $4.83 |
| 2mg | 60 tablets | $229.00 | $3.82 |
| 2mg | 90 tablets | $313.00 | $3.48 |
| 2mg | 100 tablets | $341.00 | $3.41 |
| 2mg | 200 tablets | $620.00 | $3.10 |
| 2mg | 300 tablets | $903.00 | $3.01 |
- Category
- Digestive Health
- Active ingredient
- Prucalopride
- Route
- Oral use
- Form
- Tablet
- Strengths
- 1mg · 2mg
Motegrity is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Motegrity on your behalf.
- Condition
- Chronic Idiopathic Constipation
- Alternative names
- prucalopride
- Therapeutic class
- Selective 5-HT4 Receptor Agonist
- Pharmacological class
- Prokinetic Agent
- Minor side effects
- headache; nausea; diarrhoea
- Moderate side effects
- abdominal pain; decreased appetite; fatigue
- Serious side effects
- severe depression and suicidal ideation, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Shire
- Onset time
- 24–48 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Erythromycin; Ketoconazole
- Age restrictions
- Approved for adults.
Contraindications
renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders
Patient summary
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
Mechanism of action
Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.
Pregnancy and breastfeeding
Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.
FAQ
Is the Motegrity on Direct Meds a generic?
Yes, you receive a generic. Motegrity is the original brand, made by Shire, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (prucalopride) at the strength you choose. The generic brand and manufacturer depend on available stock.
How is Motegrity priced?
It depends on the strength and pack. Motegrity comes in 1mg and 2mg strengths, in packs of 30 to 300 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What is Motegrity used for?
Motegrity contains prucalopride, used for chronic idiopathic constipation.
How quickly does Motegrity work?
Prucalopride usually starts to work within 24 to 48 hours, and its effect lasts about 24 hours. How quickly it works can differ from one person to another.
Does Motegrity have side effects?
Yes. The common side effects of prucalopride are headache, nausea and diarrhoea. Less common ones include abdominal pain, decreased appetite and fatigue. Serious but less common side effects include severe depression and suicidal ideation, which need urgent medical attention.
Which medicines interact with Motegrity?
Prucalopride can interact with erythromycin and ketoconazole. Tell your doctor or pharmacist about every medicine you take before you start taking Motegrity.
Can I buy Motegrity over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Motegrity. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Motegrity online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Motegrity names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Prucalopride at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.