
Motegrity
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
- Category
- Digestive Health
- Active ingredient
- Prucalopride
- Route
- Oral use
- Form
- Tablet
- Strengths
- 1mg · 2mg
Motegrity is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Motegrity depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Motegrity details
- Condition
- Chronic Idiopathic Constipation
- Alternative names
- prucalopride
- Therapeutic class
- Selective 5-HT4 Receptor Agonist
- Pharmacological class
- Prokinetic Agent
- Minor side effects
- headache; nausea; diarrhoea
- Moderate side effects
- abdominal pain; decreased appetite; fatigue
- Serious side effects
- severe depression and suicidal ideation, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Shire
- Onset Time
- 24–48 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Erythromycin; Ketoconazole
- Age restrictions
- Approved for adults.
Contraindications
renal impairment requiring dialysis; intestinal perforation; obstructive bowel disorders
Patient summary
Prucalopride tablets for chronic constipation. It stimulates the bowel's own nerves to get things moving again.
Mechanism of action
Stimulates 5-HT4 receptors in gut walls, enhancing peristaltic contractions to optimise bowel movement frequency.
Pregnancy and breastfeeding
Pregnancy: Limited clinical records. Avoid in pregnancy. Breastfeeding: Expelled in low amounts.
What you will receive
Motegrity names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Prucalopride at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.