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Zyloprim

Zyloprim

Allopurinol

Allopurinol tablets for gout and high uric acid. It reduces the amount of uric acid the body makes, helping to prevent flare-ups.

All strengths and pack prices
StrengthPackPricePer unit
100mg180 tablets$117.00$0.65
100mg270 tablets$164.00$0.61
100mg360 tablets$206.00$0.57
300mg60 tablets$79.00$1.32
300mg90 tablets$97.00$1.08
300mg120 tablets$118.00$0.98
300mg180 tablets$155.00$0.86
300mg270 tablets$210.00$0.78
300mg360 tablets$265.00$0.74
Active ingredient
Allopurinol
Route
Oral use
Form
Tablet
Strengths
100mg · 300mg

Zyloprim is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Zyloprim on your behalf.

Alternative names
allopurinol
Therapeutic class
Xanthine Oxidase Inhibitor
Pharmacological class
Uric Acid Synthesis Inhibitor
Known off-label uses
calcium oxalate calculi prevention
Contraindications
severe hypersensitivity to allopurinol
Minor side effects
nausea; headache; mild skin rash
Moderate side effects
diarrhoea; elevated liver enzymes; acute gout flare during initiation
Dosage forms
Tablet
Administration route
Oral use
Originator
GlaxoSmithKline
Onset time
1–2 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Azathioprine; Mercaptopurine; Warfarin
Age restrictions
Approved for paediatric and adult populations based on indication.
Serious side effects

allopurinol hypersensitivity syndrome, requires immediate medical attention; severe bone marrow suppression, requires immediate medical attention

Patient summary

Allopurinol tablets for gout and high uric acid. It reduces the amount of uric acid the body makes, helping to prevent flare-ups.

Mechanism of action

Inhibits xanthine oxidase, preventing the physiological conversion of hypoxanthine and xanthine to uric acid.

Pregnancy and breastfeeding

Pregnancy: Use if potential benefits outweigh risks. Breastfeeding: Expelled in milk; monitor infant.

FAQ

Is the Zyloprim sold here the original brand?

No. Zyloprim is the original brand, made by GlaxoSmithKline, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (allopurinol) at the strength you choose. The generic brand and manufacturer depend on available stock.

How is Zyloprim priced?

It depends on the strength and pack. Zyloprim comes in 100mg and 300mg strengths, in packs of 60 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

What are the brand names for allopurinol in South Africa?

In South Africa, allopurinol is also sold under brand names such as Puricos and Zorikos.

What is Zyloprim used for?

Zyloprim contains allopurinol, used for gouty arthritis and hyperuricaemia.

When does Zyloprim start working?

Allopurinol usually starts to work within 1 to 2 weeks. The exact timing differs between people.

What are the side effects of Zyloprim?

The common side effects of allopurinol are nausea, headache and mild skin rash. Less common ones include diarrhoea, elevated liver enzymes and acute gout flare during initiation. Serious but less common side effects include allopurinol hypersensitivity syndrome and severe bone marrow suppression, which need urgent medical attention.

Which medicines interact with Zyloprim?

Allopurinol can interact with azathioprine, mercaptopurine and warfarin. Tell your doctor or pharmacist about every medicine you take before you start taking Zyloprim.

Can I buy Zyloprim over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Zyloprim. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Zyloprim in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Zyloprim names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Allopurinol at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics