Imiquimod (Aldara)

Buy Imiquimod (Aldara)
Imiquimod (Aldara)

$46.74

Imiquimod (Aldara) 5% is a topical immune response modifier used for the localised non-surgical treatment of external genital warts, actinic keratosis, and superficial basal cell carcinoma. It is intended for application directly onto affected skin areas as prescribed by a specialist. Imiquimod works by stimulating the skin's own immune system to mount a localised defence against abnormal cells or viral lesions. Imiquimod (Aldara) 5% cream is available to order from our online pharmacy with secure delivery to South Africa.

Table of contents

Imiquimod (Aldara) Buyer and Patient Handbook - South Africa

What is Imiquimod (Aldara)?

Imiquimod (Aldara) is a topical immune response modifier marketed as a 5 % cream and classified under antiviral, cancer-support and hair-skin-care therapies. It is approved for the treatment of external genital warts, actinic keratoses, and superficial basal-cell carcinoma. The product complies with Health Products Regulatory Authority (HPRA) standards and is available in a single-use tube.

Who Should Use Imiquimod (Aldara)?

  • Adults (≥18 years) with clinically diagnosed external genital warts.
  • Patients with actinic keratoses on the face or scalp that are not amenable to surgical removal.
  • Individuals diagnosed with superficial basal-cell carcinoma confirmed by biopsy.
  • Immunocompetent persons who can safely apply a topical medication to the skin.

How Does It Work?

Imiquimod activates Toll-like receptor 7 (TLR-7) on immune cells, triggering the production of interferon-α, tumour necrosis factor-α and other cytokines. This “wake-up” signal recruits immune cells to the application site, causing viral-infected or dysplastic cells to be recognized and destroyed. Think of it as a local fire alarm that summons the body's own security team to clear the problem area.

Safety note: Imiquimod is not a systemic drug and has no significant abuse potential.

Why Choose Imiquimod (Aldara)?

  • Proven efficacy: Clinical trials show clearance rates of 70-80 % for genital warts after 16 weeks of treatment.
  • Non-invasive: Avoids surgery, cryotherapy or laser, which can cause scarring.
  • Convenient at-home use: Patients apply the cream themselves, fitting treatment into daily routines.

Off-label uses (e.g., lentigo maligna, Molluscum Contagiosum) should only be undertaken after professional consultation.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • Genital warts: Apply a thin layer to the affected area once daily, 5 days per week (e.g., Monday-Friday).
  • Actinic keratoses: Apply once daily, 5 days per week, for up to 4 weeks.
  • Superficial basal-cell carcinoma: Apply once daily, 5 days per week, for 6 weeks.

How to Take

  1. Wash and dry the treatment area.
  2. Dispense a pea-sized amount of cream (≈.5 g) and spread evenly to a thin film.
  3. Allow the cream to dry (≈30 minutes) before covering with clothing.
  4. Wash hands thoroughly after each application.

Missed Dose

If you forget a dose, apply it as soon as you remember provided the next scheduled dose is at least 12 hours away. Skip the missed dose if the next application is within a few hours to maintain the 5-day-week schedule.

Overdose

Excessive application may increase local skin irritation. Rinse the area with mild soap and water and discontinue use. If severe redness, blistering or systemic symptoms develop, seek urgent medical care.

Special Populations

  • Elderly: Skin may be more fragile; use a thinner layer and monitor for irritation.
  • Pregnancy & lactation: Use only if the benefit clearly outweighs potential risk; discuss with a health professional.
  • Renal/hepatic impairment: No dosage adjustment needed, but monitor skin response closely.

Lifestyle & Diet

  • Avoid applying the cream to healthy skin, mucous membranes, or open wounds.
  • Do not use tanning beds or UV lamps while treatment is ongoing.
  • Grapefruit juice does not affect topical Imiquimod, but maintain a balanced diet to support immune health.

Precautions and Warnings

  • Do not apply to broken or inflamed skin; irritation may worsen.
  • Protect treated areas from sunlight; use sunscreen (SPF 30 +) after the cream has dried.
  • If severe allergic reaction (swelling, difficulty breathing) occurs, stop treatment and seek emergency care.

Drug Interactions

Drug Class Interaction Risk Recommended Action
Topical steroids May reduce efficacy Use steroid only after Imiquimod course completed
Systemic immunosuppressants Potential reduced response Monitor closely; consider alternative therapy
Other topical antivirals Unknown synergy Apply on separate days if both required

Potential Side Effects

Common Side Effects

  • Redness and swelling at application site
  • Itching or mild burning sensation
  • Crusting or scaling

Less Common Side Effects

  • Erosion or ulceration of skin
  • Hyperpigmentation after healing
  • Localised hair loss where applied

Serious Side Effects

  • Severe skin infection (cellulitis) - contact a clinician immediately
  • Extensive blistering or necrosis - stop treatment and seek urgent care

Who Should Avoid This Medication?

  • Individuals with known hypersensitivity to Imiquimod or any cream excipients.
  • Patients with active cutaneous infections (bacterial, fungal, viral) in the target area.
  • Those with autoimmune disorders where immune activation may exacerbate disease (e.g., lupus) unless advised otherwise.

Storage Instructions

  • Keep the tube at room temperature (15-30 °C), away from direct sunlight.
  • Do not freeze; if the cream hardens, warm gently in your hands before use.
  • Keep out of reach of children and pets.

Imiquimod (Aldara) Alternatives

Name Class Key Difference
Podofilox gel Topical antiviral Direct viral DNA synthesis inhibition; used for genital warts
5-Fluorouracil cream Topical chemotherapeutic Causes cell death via DNA synthesis disruption; more irritating
Cryotherapy (liquid nitrogen) Physical ablative One-time procedure; risk of scarring, not suitable for extensive lesions

Frequently Asked Questions

How long does a typical treatment course last?

For genital warts, most patients complete 16 weeks (5 days/week) before evaluating clearance.

Can I shave the treated area while using Imiquimod?

Shaving may cause micro-abrasions that increase irritation. Avoid shaving until the treatment course is finished.

Is it safe to use moisturisers alongside Imiquimod?

Apply moisturiser at least 30 minutes after the cream has dried, and choose fragrance-free, non-oil-based products.

Will Imiquimod affect my blood sugar or cholesterol levels?

No systemic absorption has been demonstrated; it does not alter blood glucose or lipid profiles.

Can I swim or bathe after applying the cream?

Allow the cream to dry completely (≈30 minutes) before exposing the area to water. Prolonged soaking should be avoided during treatment days.

What should I do if the skin becomes very painful?

Stop the application for 2-3 days, use a gentle cool compress, and consult a healthcare professional if Pain persists.

Is Imiquimod safe for use on the face?

Yes, when prescribed for actinic keratoses or superficial basal-cell carcinoma on the face, following the exact dosage schedule.

How soon will I see results?

Visible reduction in warts or lesions typically appears 2-4 weeks into therapy, but full clearance may require the entire prescribed course.

Can I use Imiquimod if I have a pacemaker?

There is no known interaction with cardiac devices; however, discuss any concerns with your health provider.

Does Imiquimod require blood tests?

Routine blood monitoring is not required, as systemic exposure is negligible.

Glossary

  • Toll-like receptor 7 (TLR-7): A protein on immune cells that recognises viral components and triggers an antiviral response.
  • Cytokines: Small proteins released by immune cells that coordinate inflammation and defence.
  • Basal-cell carcinoma (BCC): The most common form of skin Cancer, arising from basal cells in the epidermis.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label use should only be considered after discussion with a qualified health professional. All treatment decisions are the responsibility of the reader. Our online pharmacy offers Imiquimod (Aldara) 5 % cream through a secure, regulated platform; however, we do not dispense prescriptions. Always consult a qualified clinician before initiating or altering any medication regimen.

How to Purchase Imiquimod (Aldara) | Imiquimod Through Our Online Pharmacy

Buying Imiquimod (Aldara) | Imiquimod from our online pharmacy is simple and convenient. Start by selecting the desired dosage and quantity displayed on the product page. The price updates in real-time, so you know exactly what to expect before proceeding. Click the Add to Basket button to include your selection in your cart. You can continue browsing for additional medications or proceed directly to the checkout. On the Checkout Page, finalize your purchase using our secure payment system, ensuring your details remain confidential and protected.

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