Disulfiram
Antabuse (disulfiram) is the only product on this shelf, available in 250 mg and 500 mg tablets as an alcohol deterrent used alongside treatment for Alcohol Dependence.
Medicine containing Disulfiram
Key points
- Never take disulfiram while intoxicated or without full understanding of the reaction it causes with alcohol; this is a boxed warning on the label.
- It blocks the liver enzyme that breaks down alcohol, so even small amounts in food, liquid medicine, toiletries or perfumes can trigger a severe reaction.
- Disulfiram deters drinking through a physical reaction rather than by reducing the urge to drink.
How does Disulfiram work?
Disulfiram irreversibly inactivates aldehyde dehydrogenase (ALDH), the liver enzyme that breaks down alcohol. With that enzyme blocked, a toxic by-product accumulates in the blood and produces flushing, nausea, rapid heartbeat and headache within minutes of any alcohol exposure.
The effect lasts up to 14 days after the last tablet, so alcohol and alcohol-containing products must be avoided for that period. In Addiction Recovery treatment, disulfiram also affects the enzyme that converts dopamine to noradrenaline, which adds to the overall deterrent effect.
Further reading
FAQ
What disulfiram products are available?
On Direct Meds, disulfiram comes as Antabuse. Compare their forms, strengths and packs.
How is disulfiram priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Do I need a prescription for disulfiram in South Africa?
No, not online. Direct Meds does not ask for a prescription to order disulfiram. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy disulfiram in South Africa?
On Direct Meds: choose the product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated