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Antabuse

Antabuse

Disulfiram

Disulfiram tablets for alcohol dependence. Even small amounts of alcohol in food or medicine can trigger a severe reaction.

All strengths and pack prices
StrengthPackPricePer unit
250mg90 tablets$38.00$0.42
250mg120 tablets$47.00$0.39
250mg180 tablets$67.00$0.37
250mg270 tablets$95.00$0.35
250mg360 tablets$123.00$0.34
500mg60 tablets$47.00$0.78
500mg90 tablets$62.00$0.69
500mg120 tablets$76.00$0.63
500mg180 tablets$105.00$0.58
500mg270 tablets$149.00$0.55
500mg360 tablets$195.00$0.54
Active ingredient
Disulfiram
Route
Oral use
Form
Tablet
Strengths
250mg · 500mg

Antabuse is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Antabuse on your behalf.

Alternative names
disulfiram
Therapeutic class
Aldehyde Dehydrogenase Inhibitor
Pharmacological class
Alcohol Deterrent
Contraindications
recent alcohol ingestion; severe myocardial disease; psychosis
Minor side effects
metallic taste; headache; drowsiness
Moderate side effects
fatigue; impotence; rash
Dosage forms
Tablet
Administration route
Oral use
Originator
Odyssey Pharmaceuticals
Onset time
12 hours
Duration
1–2 weeks
Storage instructions
Store below 25°C.
Drug interactions
Alcohol; Metronidazole; Phenytoin
Age restrictions
Approved for adults.
Serious side effects

severe hepatotoxicity, requires immediate medical attention; disulfiram-alcohol reaction, requires immediate medical attention

Patient summary

Disulfiram tablets for alcohol dependence. Even small amounts of alcohol in food or medicine can trigger a severe reaction.

Mechanism of action

Blocks the enzyme aldehyde dehydrogenase, causing toxic accumulation of acetaldehyde if alcohol is consumed, inducing severe discomfort.

Pregnancy and breastfeeding

Pregnancy: Avoid in pregnancy unless benefits outweigh potential fetal risks. Breastfeeding: Avoid.

FAQ

Is the Antabuse on Direct Meds a generic?

Yes, you receive a generic. Antabuse is the original brand, made by Odyssey Pharmaceuticals, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (disulfiram) at the strength you choose. The generic brand and manufacturer depend on available stock.

How is Antabuse priced?

Antabuse comes in 250mg and 500mg strengths, in packs of 60 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

What is Antabuse used for?

Antabuse contains disulfiram, used for alcohol dependence.

When does Antabuse start working?

Disulfiram usually starts to work within 12 hours. This varies from person to person.

What side effects can Antabuse cause?

The common side effects of disulfiram are metallic taste, headache and drowsiness. Less common ones include fatigue, impotence and rash. Serious but less common side effects include severe liver damage (hepatotoxicity) and disulfiram-alcohol reaction, which need urgent medical attention.

Does Antabuse interact with alcohol?

Alcohol can interact with disulfiram, so check with a doctor or pharmacist before you drink while taking Antabuse.

What does Antabuse interact with?

Disulfiram can interact with metronidazole and phenytoin. Tell your doctor or pharmacist about every medicine you take before you start taking Antabuse.

Can I buy Antabuse over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Antabuse. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Do you deliver Antabuse to South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Antabuse names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Disulfiram at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics