Efudex

Fluorouracil cream for actinic keratosis and some skin cancers. It destroys precancerous and cancerous cells by blocking their rapid division.

Dosage

Pack size

Efudex is the reference name. You receive a generic with the same active ingredient and strength.

Supply requirements for Efudex depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.

Efudex details

Conditions: Actinic Keratosis · Superficial Basal Cell Carcinoma
Alternative names: fluorouracil
Therapeutic class: Antineoplastic; Antimetabolite
Pharmacological class: Topical Fluorouracil
Minor side effects: skin erythema; burning sensation
Moderate side effects: scaling skin; swelling; hyperpigmentation
Serious side effects: severe skin ulceration, requires immediate medical attention
Dosage forms: Cream
Administration route: Cutaneous use
Supply category: Prescription-only medicine (POM)
Originator: Valeant Pharmaceuticals
Onset Time: 2–4 weeks
Duration: 12 hours
Storage instructions: Store below 25°C.
Age restrictions: Approved for adults.

Contraindications

pregnancy; dihydropyrimidine dehydrogenase (DPD) deficiency; hypersensitivity to fluorouracil

Patient summary

Fluorouracil cream for actinic keratosis and some skin cancers. It destroys precancerous and cancerous cells by blocking their rapid division.

Mechanism of action

Acts as a pyrimidine antagonist, selectively blocking DNA and RNA synthesis within rapidly dividing abnormal skin cells.

Pregnancy and breastfeeding

Pregnancy: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.

Efudex names the medicine you are looking for. What ships is a generic version of it.

A generic containing Fluorouracil at the strength you pick.
Which generic brand and maker ships depends on stock and destination.
Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.