Mysimba
Naltrexone and bupropion tablets for weight management. They work on the brain's reward system to cut food cravings.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 90mg + 8mg | 10 tablets | $106.00 | $10.60 |
| 90mg + 8mg | 20 tablets | $182.00 | $9.10 |
| 90mg + 8mg | 30 tablets | $242.00 | $8.07 |
| 90mg + 8mg | 60 tablets | $302.00 | $5.03 |
| 90mg + 8mg | 90 tablets | $376.00 | $4.18 |
| 90mg + 8mg | 120 tablets | $466.00 | $3.88 |
| 90mg + 8mg | 180 tablets | $600.00 | $3.33 |
| 90mg + 8mg | 270 tablets | $816.00 | $3.02 |
| 90mg + 8mg | 360 tablets | $1039.00 | $2.89 |
- Category
- Weight Management
- Active ingredients
- Naltrexone · Bupropion
- Route
- Oral use
- Form
- Tablet
- Strengths
- 90mg + 8mg
Mysimba is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Mysimba on your behalf.
- Condition
- Chronic Weight Management
- Alternative names
- naltrexone, bupropion
- Therapeutic class
- Opioid Antagonist, Aminoketone Antidepressant Combination
- Pharmacological class
- Weight Management Agent
- Minor side effects
- nausea; headache; constipation
- Moderate side effects
- dry mouth; insomnia; vomiting
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Orexigen Therapeutics
- Onset time
- 4–8 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- MAO Inhibitors; Opioid Analgesics; Alcohol
- Age restrictions
- Approved for adults over eighteen years.
Contraindications
uncontrolled hypertension; seizure disorders; abrupt alcohol withdrawal; MAO inhibitor therapy
Serious side effects
suicidal ideation, requires immediate medical attention; seizure activation, requires immediate medical attention
Patient summary
Naltrexone and bupropion tablets for weight management. They work on the brain's reward system to cut food cravings.
Mechanism of action
Metabolites coordinate pathways in the hypothalamic feeding center and mesolimbic reward system to lower food desires.
Pregnancy and breastfeeding
Pregnancy: Highly contraindicated. No therapeutic benefit during pregnancy. Breastfeeding: Avoid.
FAQ
Is the Mysimba sold here the original brand?
No. Mysimba is the original brand, made by Orexigen Therapeutics, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredients (naltrexone and bupropion) at the same strength. The generic brand and manufacturer depend on available stock.
How much does Mysimba cost in South Africa?
The price varies with pack size. Mysimba comes in a 90mg + 8mg strength, in packs of 10 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →Is Mysimba sold under other names?
In South Africa, naltrexone and bupropion are also sold under brand names such as Contrave.
What is Mysimba used for?
Mysimba contains naltrexone and bupropion, used for chronic weight management.
When does Mysimba start working?
Naltrexone and bupropion usually start to work within 4 to 8 weeks. How quickly they work can differ from one person to another.
Does Mysimba have side effects?
Yes. The common side effects of naltrexone and bupropion are nausea, headache and constipation. Less common ones include dry mouth, insomnia and vomiting. Serious but less common side effects include suicidal ideation and seizure activation, which need urgent medical attention.
Can I drink alcohol with Mysimba?
Alcohol can interact with naltrexone and bupropion, so check with a doctor or pharmacist before you drink while taking Mysimba.
Which medicines interact with Mysimba?
Naltrexone and bupropion can interact with MAO inhibitors and opioid analgesics. Tell your doctor or pharmacist about every medicine you take before you start taking Mysimba.
Can I buy Mysimba over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Mysimba. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy Mysimba in South Africa?
On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Mysimba names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Naltrexone / Bupropion at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.