Nexletol
Bempedoic acid tablets for high cholesterol. It lowers LDL cholesterol by blocking an early step in the liver's cholesterol production.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 180mg | 30 tablets | $121.00 | $4.03 |
| 180mg | 60 tablets | $167.00 | $2.78 |
| 180mg | 90 tablets | $212.00 | $2.36 |
| 180mg | 120 tablets | $257.00 | $2.14 |
| 180mg | 180 tablets | $348.00 | $1.93 |
- Category
- Heart & Blood Pressure
- Active ingredient
- Bempedoic Acid
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 180mg
Nexletol is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Nexletol on your behalf.
- Conditions
- Primary Hypercholesterolaemia · Mixed Dyslipidaemia
- Alternative names
- Nilemdo
- Therapeutic class
- Adenosine triphosphate-citrate lyase inhibitor
- Pharmacological class
- Lipid-lowering agent
- Contraindications
- hypersensitivity to bempedoic acid; pregnancy; breastfeeding
- Minor side effects
- hyperuricaemia; muscle spasms; back pain; abdominal pain
- Moderate side effects
- gout; anaemia; increased liver enzymes
- Serious side effects
- tendon rupture, requires immediate medical attention
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Daiichi Sankyo
- Onset time
- 2–4 weeks
- Duration
- Ongoing
- Storage instructions
- Store below 30°C.
- Drug interactions
- Simvastatin; Pravastatin
- Age restrictions
- Not for use in children.
- Pregnancy and breastfeeding
- Pregnancy: Contraindicated. Breastfeeding: Do not use during breastfeeding.
Precautions and warnings
monitor uric acid levels; caution in patients with history of gout; monitor for tendon rupture
Patient summary
Bempedoic acid tablets for high cholesterol. It lowers LDL cholesterol by blocking an early step in the liver's cholesterol production.
Mechanism of action
Bempedoic acid inhibits ATP-citrate lyase, an enzyme involved in cholesterol biosynthesis in the liver, resulting in reduced LDL-cholesterol levels in the blood.
FAQ
Is the Nexletol on Direct Meds a generic?
Yes, you receive a generic. Nexletol is the original brand, made by Daiichi Sankyo, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (bempedoic acid) at the same strength. The generic brand and manufacturer depend on available stock.
What is another name for bempedoic acid?
Other brand names for bempedoic acid include Nilemdo.
How much does Nexletol cost in South Africa?
The price varies with pack size. Nexletol comes in a 180mg strength, in packs of 30 to 180 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What is Nexletol used for?
Nexletol contains bempedoic acid, used for primary hypercholesterolaemia and mixed dyslipidaemia.
How long does Nexletol take to work?
Bempedoic acid usually starts to work within 2 to 4 weeks. How quickly it works can differ from one person to another.
What side effects can Nexletol cause?
The common side effects of bempedoic acid are hyperuricaemia, muscle spasms, back pain and abdominal pain. Less common ones include gout, anaemia and increased liver enzymes. Serious but less common side effects include tendon rupture, which needs urgent medical attention.
What does Nexletol interact with?
Bempedoic acid can interact with simvastatin and pravastatin. Tell your doctor or pharmacist about every medicine you take before you start taking Nexletol.
Do I need a prescription to buy Nexletol in South Africa?
No, not online: Direct Meds does not ask for a prescription to order Nexletol. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy Nexletol in South Africa?
On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Nexletol names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Bempedoic Acid at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.