Topamax
Topiramate tablets for seizures and migraine prevention. It calms overactive nerve signals in the brain.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 25mg | 30 tablets | $85.00 | $2.83 |
| 25mg | 60 tablets | $141.00 | $2.35 |
| 25mg | 90 tablets | $192.00 | $2.13 |
| 25mg | 120 tablets | $231.00 | $1.93 |
| 25mg | 180 tablets | $318.00 | $1.77 |
| 25mg | 360 tablets | $582.00 | $1.62 |
| 50mg | 30 tablets | $79.00 | $2.63 |
| 50mg | 60 tablets | $127.00 | $2.12 |
| 50mg | 90 tablets | $176.00 | $1.96 |
| 50mg | 120 tablets | $209.00 | $1.74 |
| 50mg | 180 tablets | $282.00 | $1.57 |
| 50mg | 240 tablets | $341.00 | $1.42 |
| 50mg | 360 tablets | $460.00 | $1.28 |
| 100mg | 30 tablets | $102.00 | $3.40 |
| 100mg | 60 tablets | $164.00 | $2.73 |
| 100mg | 90 tablets | $227.00 | $2.52 |
| 100mg | 120 tablets | $290.00 | $2.42 |
| 100mg | 180 tablets | $415.00 | $2.31 |
| 100mg | 270 tablets | $603.00 | $2.23 |
| 200mg | 30 tablets | $118.00 | $3.93 |
| 200mg | 60 tablets | $187.00 | $3.12 |
| 200mg | 90 tablets | $257.00 | $2.86 |
| 200mg | 120 tablets | $327.00 | $2.73 |
| 200mg | 180 tablets | $467.00 | $2.59 |
- Category
- Neurology
- Active ingredient
- Topiramate
- Route
- Oral use
- Form
- Tablet
- Strengths
- 25mg · 50mg · 100mg · 200mg
Topamax is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Topamax on your behalf.
- Conditions
- Seizure Disorders · Migraine Headache Prophylaxis
- Alternative names
- topiramate
- Therapeutic class
- Sulfamate-Substituted Monosaccharide Anticonvulsant
- Pharmacological class
- Antiepileptic Agent
- Known off-label uses
- bipolar disorder; obesity
- Contraindications
- metabolic acidosis; hypersensitivity to topiramate
- Minor side effects
- paraesthesia; somnolence; fatigue
- Moderate side effects
- cognitive slowing; anorexia; weight loss
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Janssen Pharmaceuticals
- Onset time
- 2–4 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C. Keep dry.
- Drug interactions
- Valproic Acid; Oral Contraceptives; Phenytoin
- Age restrictions
- Approved for children over two years and adults based on indication.
Serious side effects
acute myopia and secondary angle-closure glaucoma, requires immediate medical attention; suicidal ideation, requires immediate medical attention; metabolic acidosis, requires immediate medical attention
Patient summary
Topiramate tablets for seizures and migraine prevention. It calms overactive nerve signals in the brain.
Mechanism of action
Blocks voltage-dependent sodium channels, enhances GABA-A activity, and antagonises glutamate receptors.
Pregnancy and breastfeeding
Pregnancy: High risk of oral clefts in newborn. Avoid. Breastfeeding: Expelled in milk.
FAQ
Is the Topamax sold here the original brand?
No. Topamax is the original brand, made by Janssen Pharmaceuticals, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (topiramate) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Topamax cost in South Africa?
Topamax comes in 25mg, 50mg, 100mg and 200mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What other names is Topamax sold under?
In South Africa, topiramate is also sold under brand names such as Toplep, Topalex and Epitoz.
What is Topamax used for?
Topamax contains topiramate, used for seizure disorders and migraine headache prophylaxis.
How long does Topamax take to work?
Topiramate usually starts to work within 2 to 4 weeks. This varies from person to person.
What are the side effects of Topamax?
The common side effects of topiramate are paraesthesia, drowsiness (somnolence) and fatigue. Less common ones include cognitive slowing, loss of appetite and weight loss. Serious but less common side effects include acute myopia and secondary angle-closure glaucoma, suicidal ideation and metabolic acidosis, which need urgent medical attention.
Which medicines interact with Topamax?
Topiramate can interact with valproic acid, oral contraceptives and phenytoin. Tell your doctor or pharmacist about every medicine you take before you start taking Topamax.
Is Topamax available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Topamax. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy Topamax in South Africa?
On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Topamax names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Topiramate at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.