Zofran
Ondansetron tablets for nausea and vomiting after chemotherapy or surgery. It blocks a chemical that triggers the vomiting reflex.
- Category
- Oncology Support
- Active ingredient
- Ondansetron
- Route
- Oral use
- Form
- Tablet
- Strengths
- 4mg · 8mg
Zofran is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Zofran depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Zofran details
- Alternative names
- ondansetron
- Therapeutic class
- 5-HT3 Receptor Antagonist
- Pharmacological class
- Antiemetic
- Known off-label uses
- gastroenteritis-associated vomiting
- Contraindications
- concurrent apomorphine use; hypersensitivity to ondansetron
- Minor side effects
- headache; constipation; fatigue
- Moderate side effects
- dizziness; mild rash; transient transaminase elevation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- GlaxoSmithKline
- Onset Time
- 30–60 minutes
- Duration
- 8–12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Apomorphine; QT-prolonging drugs
- Age restrictions
- Approved for paediatric and adult populations based on formulation.
Serious side effects
QT prolongation, requires immediate medical attention; serotonin syndrome, requires immediate medical attention
Patient summary
Ondansetron tablets for nausea and vomiting after chemotherapy or surgery. It blocks a chemical that triggers the vomiting reflex.
Mechanism of action
Blocks peripheral and central 5-HT3 receptors on vagal nerve terminals and the chemoreceptor trigger zone in brain tissues.
Pregnancy and breastfeeding
Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Consult a doctor.
What you will receive
Zofran names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Ondansetron at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.