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Cobra-120 (Sildenafil) Buyer and Patient Handbook in South Africa

Cobra-120 (Sildenafil) is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of Erectile Dysfunction in adult men. It is approved by the South African Health Products Regulatory Authority (SAHPRA) and is available as an oral pill.

What is Cobra-120?

Cobra-120 contains the active ingredient sildenafil, a medication that belongs to the PDE5 inhibitor class. It is used to improve erectile function in men with erectile dysfunction. The product is supplied as a 120 mg tablet and carries SAHPRA, FDA, and EMA approval for safety and efficacy.

Who Should Use Cobra-120?

• Adult men diagnosed with erectile dysfunction
• Individuals who have tried non-pharmacological approaches without sufficient result
• Men who are stable on antihypertensive therapy and have no contraindications listed below

How Does It Work?

Sildenafil blocks the enzyme PDE5, which normally degrades cyclic guanosine monophosphate (cG-c). By inhibiting PDE5, cG-c levels rise, leading to smooth-muscle relaxation in the penile arteries and increased blood flow during sexual stimulation. The effect only occurs with sexual arousal, so the medication does not cause an erection without stimulation. Abuse potential is low, but the drug should not be taken more than once per day.

Why Choose Cobra-120?

Cobra-120 delivers a high-strength 120 mg dose, providing a longer duration of action compared with lower-dose options. It offers a convenient once-daily regimen for men who need reliable performance on demand. Generic alternatives containing sildenafil are also available and may be more cost-effective, but Cobra-120’s consistent bioavailability ensures predictable results.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 120 mg taken as needed before sexual activity.
• Do not exceed one tablet per 24-hour period.

How to Take

1. Swallow the tablet whole with a glass of water.
2. Take it 30 minutes to 2 hours before planned sexual activity.
3. Sexual stimulation is required for the medication to work.

Missed Dose

If you miss a dose because you did not engage in sexual activity, no additional tablet is needed. Wait for the next opportunity and take the regular dose, ensuring a 24-hour gap between doses.

Overdose

If you suspect an overdose (e.g., taking more than one tablet), seek urgent medical attention. Symptoms may include low blood pressure, dizziness, or visual disturbances.

Special Populations

• Elderly (≥65 years): Start with a lower dose (50 mg) and titrate up if tolerated.
• Renal or hepatic impairment: Dose reduction may be required; consult a healthcare professional.
• Women and children: Not approved for these groups.

Lifestyle & Diet

• Avoid large amounts of grapefruit juice as it can increase sildenafil levels.
• Alcohol in moderation is acceptable, but excessive intake may reduce the drug’s effectiveness.
• Do not use nitrates (e.g., nitroglycerin) as the combination can cause dangerous blood-pressure drops.

Precautions and Warnings

• Do not use if you have a known allergy to sildenafil or any component of the tablet.
• Cardiovascular risk: Men with unstable Angina, recent myocardial infarction, or severe Heart Failure should avoid this medication.
• Vision problems: Rarely, sildenafil can cause non-arteritic anterior ischemic optic neuropathy; discontinue and seek care if sudden vision loss occurs.
• Priapism: An erection lasting longer than 4 hours requires immediate medical attention.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less Common Side Effects

• Dizziness
• Muscle aches
• Vision colour changes (blue/green tint)

Serious Side Effects

• Chest Pain or irregular heartbeat - stop and seek emergency care
• Sudden vision loss - consult an ophthalmologist immediately
• Prolonged erection (≥4 hours) - call emergency services

Who Should Avoid This Medication?

• Men taking nitrates for chest pain
• Individuals with severe uncontrolled hypertension
• Patients with a history of non-arteritic anterior ischemic optic neuropathy
• Men with known hypersensitivity to sildenafil or any tablet excipient

Storage Instructions

• Keep the tablet below 30 °C (86 °F), away from direct sunlight.
• Store in the original container to protect from moisture.
• Keep out of reach of children and pets.

Cobra-120 Alternatives

Frequently Asked Questions

How long does Cobra-120's effect last?

The therapeutic effect can last up to 12 hours after a single dose, depending on individual response and activity level.

Can I take Cobra-120 with alcohol?

Moderate alcohol consumption does not usually interfere, but heavy drinking may diminish the drug’s effectiveness and increase side-effects like dizziness.

Is it safe to use Cobra-120 if I have high blood pressure?

Yes, if your blood pressure is well-controlled and you are not on nitrate therapy. Uncontrolled hypertension warrants medical review before use.

What should I do if I experience a headache?

Headaches are common and often mild; you can treat them with over-the-counter analgesics such as paracetamol, unless contraindicated.

Can Cobra-120 be taken daily?

It can be taken daily, but the recommended dose for daily use is usually 50 mg. Consult a healthcare professional before adopting a daily regimen.

Does Cobra-120 protect against sexually transmitted infections?

No, the medication only improves erectile function; it does not provide any protection against STIs.

Will smoking affect the efficacy of Cobra-120?

Smoking can impair blood flow, potentially reducing the drug’s effectiveness. Quitting smoking is advisable for optimal results.

Is there a risk of dependency on Cobra-120?

Physical dependence is not typical, though psychological reliance on any performance-enhancing medication can develop. Use as directed and discuss any concerns with a healthcare professional.

Glossary

• PDE5 inhibitor: A drug class that blocks the enzyme phosphodiesterase-5, enhancing blood flow to the penis.
• cG-MP: Cyclic guanosine monophosphate, a messenger that relaxes smooth muscle tissue.
• Priapism: A painful erection lasting longer than four hours, requiring urgent care.

Disclaimer

The information provided here is for educational purposes only and does not replace professional medical advice. All uses of Cobra-120 should be discussed with a qualified healthcare provider, especially when considering off-label applications or potential drug interactions. Our online pharmacy platform supplies the medication in compliance with South African regulations, but users remain responsible for adhering to safe usage practices. Always seek immediate medical attention for serious side effects or emergencies.