Skip to content
Diane 35

Diane 35

Cyproterone Acetate · Ethinylestradiol

Cyproterone and ethinylestradiol tablets for acne and contraception. It blocks the effect of male hormones that cause acne.

Route
Oral use
Form
Tablet
Strengths
0.035mg + 2mg

Diane 35 is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Diane 35 on your behalf.

Alternative names
cyproterone acetate, ethinyl estradiol
Therapeutic class
Androgen Receptor Antagonist, Oestrogen Combination
Pharmacological class
Oral Contraceptive and Antiandrogen
Contraindications
deep vein thrombosis; pregnancy; smoking over thirty-five years of age
Minor side effects
nausea; headache; breast tenderness
Moderate side effects
fluid retention; weight change; mood swing
Dosage forms
Tablet
Administration route
Oral use
Originator
Bayer
Onset Time
1–7 days
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Rifampin; Anticonvulsants; St. John's Wort
Age restrictions
Approved for post-menarche females.
Serious side effects

venous thromboembolism, requires immediate medical attention; stroke, requires immediate medical attention

Patient summary

Cyproterone and ethinylestradiol tablets for acne and contraception. It blocks the effect of male hormones that cause acne.

Mechanism of action

Cyproterone blocks androgen receptors, reducing sebum output, while ethinyl estradiol suppresses ovarian steroidogenesis.

Pregnancy and breastfeeding

Pregnancy: Highly contraindicated. Causes severe endocrine disturbance in fetus. Breastfeeding: Not recommended.

Is the Diane 35 on Direct Meds a generic?

Yes, you receive a generic. Diane 35 is the original brand, made by Bayer, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredients (cyproterone acetate and ethinylestradiol) at the same strength. The generic brand and manufacturer depend on available stock.

How is Diane 35 priced?

It depends on the pack size. Diane 35 comes in a 0.035mg + 2mg strength, in packs of 21 to 84 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.

Payment and prices →

What is Diane 35 used for?

Diane 35 contains cyproterone acetate and ethinylestradiol, used for androgen-dependent acne, contraception and hirsutism.

How quickly does Diane 35 work?

Cyproterone acetate and ethinylestradiol usually start to work within 1 to 7 days. How quickly they work can differ from one person to another.

What side effects can Diane 35 cause?

The common side effects of cyproterone acetate and ethinylestradiol are nausea, headache and breast tenderness. Less common ones include fluid retention, weight change and mood swings. Serious but less common side effects include venous thromboembolism and stroke, which need urgent medical attention.

What does Diane 35 interact with?

Cyproterone acetate and ethinylestradiol can interact with rifampicin, anticonvulsants and St John's wort. Tell your doctor or pharmacist about every medicine you take before you start taking Diane 35.

Is Diane 35 available over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Diane 35. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Do you deliver Diane 35 to South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Diane 35 names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Cyproterone Acetate / Ethinylestradiol at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics