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Xalatan .005% (Latanoprost) Buyer and Patient Handbook in South Africa

What is Xalatan .005%?

Xalatan .005% is a prostaglandin analogue eye-drop used to lower intra-ocular pressure in Glaucoma and ocular hypertension. It belongs to the class of prostaglandin F-type analogues and is supplied in a 2.5 ml bottle. In South Africa the product carries FDA and EMA approval and is registered with the South African Health Products Regulatory Authority (SAHPRA).

Who Should Use Xalatan .005%?

• Adults diagnosed with open-angle glaucoma or ocular hypertension.
• Patients who need once-daily pressure control to protect optic nerve health.
• Individuals seeking an off-label option for enhanced eyelash growth (after medical discussion).

How Does It Work?

Latanoprost mimics prostaglandin F₂α, binding to FP receptors in the eye’s out-flow pathway. This increases uveoscleral drainage, thereby reducing intra-ocular pressure. Think of the eye’s fluid system as a traffic network; the drug opens extra lanes, easing congestion and preventing damage to the optic “highway.”

Why Choose Xalatan .005%?

• Proven efficacy: Clinical trials show a 25-30 % reduction in eye-pressure within weeks.
• Convenient dosing: One drop nightly is all that is required.
• Brand reliability: The formulation is preservative-free, reducing irritation risk compared with some generics.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

One drop (≈ .05 ml) into the affected eye(s) once daily, preferably at night.

How to Take

1. Wash hands and avoid touching the tip of the bottle.
2. Tilt the head back, pull down the lower eyelid to create a pocket.
3. Instill a single drop without blinking for at least 30 seconds.
4. Close the eye gently and press the inner corner for 1 minute to limit systemic absorption.

Missed Dose

If a dose is missed, apply it as soon as remembered unless it is close to the next scheduled dose; then skip the missed one and continue with the regular schedule.

Overdose

If more than one drop is accidentally administered, rinse the eye with plenty of water and seek medical advice if irritation persists.

Special Populations

• Elderly: No dose adjustment needed, but monitor pressure more frequently.
• Pregnancy & breastfeeding: Use only if the potential benefit outweighs risk; limited data are available.
• Renal or hepatic impairment: No dosage change required, but routine monitoring is advised.

Lifestyle & Diet

• Avoid direct contact with water in the eyes for at least 15 minutes after instillation.
• Grapefruit juice does not interact with latanoprost, but maintain a balanced diet.
• Alcohol does not affect efficacy but excessive intake may worsen eye health.

Precautions and Warnings

• Do not use if you are allergic to latanoprost or any component of the bottle.
• Inform your eye-care professional of any history of Uveitis, ocular infection, or recent eye surgery.
• Do not apply to a contact lens; insert lenses after the drop has been absorbed.

Drug Interactions

Potential Side Effects

Common Side Effects

• Mild eye irritation or redness
• Temporary blurred vision after dosing
• Darkening of iris color (gradual)

Less Common Side Effects

• Periocular skin hyperpigmentation
• Eyelash growth or thickening
• Eye Pain or headache

Serious Side Effects

• Persistent eye pain, vision loss, or inflammation - call a doctor immediately.

Who Should Avoid This Medication?

• Individuals with known hypersensitivity to latanoprost or any excipient.
• Patients with active ocular infection or inflammation.
• Those who have had recent ocular trauma or surgery without clearance.

Storage Instructions

• Keep the bottle at room temperature (15-30 °C).
• Store away from direct sunlight and heat sources.
• Keep the cap tightly closed; discard after 6 weeks of opening even if the bottle appears full.

Xalatan .005% Alternatives

Frequently Asked Questions

How long does it take to see a pressure-lowering effect?

Most patients notice a reduction within 2 weeks, with maximal effect after 4-6 weeks.

Can I use Xalatan if I wear contact lenses?

Insert lenses after the drop has been absorbed; otherwise, remove lenses before dosing.

Will my iris colour change permanently?

Yes, the darkening is usually permanent but does not affect vision.

Is it safe to use both Xalatan and artificial tears?

Yes, apply artificial tears at least 5 minutes after the prostaglandin drop.

What should I do if I experience eye redness after dosing?

Blink several times and gently massage the inner corner; if redness persists beyond 30 minutes, seek advice.

Can Xalatan be used in both eyes simultaneously?

Apply one drop to each eye if prescribed for bilateral treatment.

Does alcohol consumption affect the medication?

Moderate alcohol does not interfere with efficacy, but heavy drinking can compromise overall eye health.

Why did my eyelashes become longer?

Latanoprost stimulates hair follicles, a known off-label effect that some patients find desirable.

Glossary

• Intra-ocular pressure (IOP): Fluid pressure inside the eye; high levels can damage the optic nerve.
• Uveoscleral out-flow: The secondary pathway through which aqueous humor leaves the eye.
• FP receptor: Cellular receptor that mediates prostaglandin-induced fluid drainage.

Disclaimer

The information provided here is for general educational purposes and reflects current knowledge about Xalatan .005% (Latanoprost). It does not replace professional medical advice. Off-label uses should be discussed with a qualified eye-care practitioner. Our online pharmacy offers convenient access to this medication, but the final decision to use it rests with you and your health-care provider. Always consult a doctor before starting or stopping any eye treatment.