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Endometrial Hyperplasia

Endometrial hyperplasia is an overgrowth of the lining of the uterus. It can sometimes progress to uterine cancer, and is confirmed by an endometrial biopsy.

Provera

Medroxyprogesterone Acetate

2.5mg · 5mg · 10mg

Medroxyprogesterone acetate tablets for missed periods and irregular bleeding. They are a synthetic progesterone that stabilises the uterine lining.

From$0.43/ tabletView

Progesterone Capsules

Progesterone

200mg

Progesterone capsules for missed periods and endometrial hyperplasia. They deliver the same hormone the body makes, helping to regulate the menstrual cycle.

From$0.69/ capsuleView

Prometrium

Progesterone

100mcg · 200mcg

Progesterone tablets for secondary amenorrhoea and endometrial hyperplasia. They are often used alongside oestrogen to protect the uterine lining.

From$1.76/ tabletView

Key points

  • The most common symptom is abnormal vaginal bleeding, though some people have no symptoms at all.
  • Treatment usually involves progesterone to reduce cancer risk, with repeat biopsies every few months.
  • Hyperplasia without atypia may resolve on its own, but atypical hyperplasia carries a substantial risk of becoming cancerous.

Medicines listed for Endometrial Hyperplasia

The listed products contain progesterone and medroxyprogesterone acetate, both of which are progestogen hormones. Progesterone appears here as a capsule and a tablet; medroxyprogesterone acetate is listed as a tablet. Progestogens oppose the growth-stimulating effect of estrogen on the lining of the uterus, and treatment for this condition usually involves progesterone to reduce cancer risk.

Further reading