Prometrium
Progesterone tablets for secondary amenorrhoea and endometrial hyperplasia. They are often used alongside oestrogen to protect the uterine lining.
- Category
- Hormone Therapy
- Active ingredient
- Progesterone
- Route
- Oral use
- Form
- Soft Gelatin Capsule
- Strengths
- 100mg · 200mg
Prometrium is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Prometrium on your behalf.
- Conditions
- Secondary Amenorrhoea · Endometrial Hyperplasia
- Alternative names
- progesterone
- Therapeutic class
- Progestogen
- Pharmacological class
- Progesterone Derivative
- Contraindications
- history of deep vein thrombosis; breast cancer; unexplained vaginal bleeding
- Minor side effects
- drowsiness; headache; breast tenderness
- Moderate side effects
- fluid retention; weight changes; mood changes
- Serious side effects
- deep vein thrombosis, requires immediate medical attention
- Dosage forms
- Soft Gelatin Capsule
- Administration route
- Oral use
- Originator
- Abbott
- Onset Time
- 24–48 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Rifampin; Ketoconazole
- Age restrictions
- Approved for adult females.
Patient summary
Progesterone tablets for secondary amenorrhoea and endometrial hyperplasia. They are often used alongside oestrogen to protect the uterine lining.
Mechanism of action
Enters target cells to bind progesterone receptors, transforming proliferative tissue into stable secretory tissue.
Pregnancy and breastfeeding
Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Consult a doctor.
Is the Prometrium on Direct Meds a generic?
Yes, you receive a generic. Prometrium is the original brand, made by Abbott, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (progesterone) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Prometrium cost in South Africa?
The price varies with strength and pack size. Prometrium comes in 100mg and 200mg strengths, in packs of 30 to 270 capsules, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per capsule.
Payment and prices →Is Prometrium sold under other names?
On Direct Meds the same ingredient is also sold as Progesterone Capsules.
What is Prometrium used for?
Prometrium contains progesterone, used for secondary amenorrhoea and endometrial hyperplasia.
When does Prometrium start working?
Progesterone usually starts to work within 24 to 48 hours, and its effect lasts about 24 hours. How quickly it works can differ from one person to another.
Does Prometrium have side effects?
Yes. The common side effects of progesterone are drowsiness, headache and breast tenderness. Less common ones include fluid retention, weight changes and mood changes. Serious but less common side effects include deep vein thrombosis, which needs urgent medical attention.
Which medicines interact with Prometrium?
Progesterone can interact with rifampicin and ketoconazole. Tell your doctor or pharmacist about every medicine you take before you start taking Prometrium.
Is Prometrium available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Prometrium. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Prometrium online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Prometrium names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Progesterone at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.