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Diflucan

Diflucan

Fluconazole

Fluconazole tablets for yeast infections, including vaginal thrush. It prevents the fungus from building its cell wall.

All strengths and pack prices
StrengthPackPricePer unit
50mg60 tablets$94.00$1.57
50mg90 tablets$125.00$1.39
50mg120 tablets$155.00$1.29
50mg180 tablets$219.00$1.22
50mg270 tablets$314.00$1.16
50mg360 tablets$405.00$1.13
100mg30 tablets$95.00$3.17
100mg60 tablets$142.00$2.37
100mg90 tablets$188.00$2.09
100mg120 tablets$235.00$1.96
100mg180 tablets$329.00$1.83
100mg270 tablets$469.00$1.74
150mg30 tablets$83.00$2.77
150mg60 tablets$125.00$2.08
150mg90 tablets$164.00$1.82
150mg120 tablets$207.00$1.73
150mg180 tablets$288.00$1.60
150mg270 tablets$410.00$1.52
200mg30 tablets$107.00$3.57
200mg60 tablets$154.00$2.57
200mg90 tablets$201.00$2.23
200mg120 tablets$249.00$2.08
200mg180 tablets$342.00$1.90
200mg270 tablets$487.00$1.80
400mg30 tablets$177.00$5.90
400mg60 tablets$266.00$4.43
400mg90 tablets$355.00$3.94
400mg120 tablets$445.00$3.71
400mg180 tablets$622.00$3.46
400mg270 tablets$888.00$3.29
Category
Antifungals
Active ingredient
Fluconazole
Route
Oral use
Form
Tablet
Strengths
50mg · 100mg · 150mg · 200mg · 400mg

Diflucan is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Diflucan on your behalf.

Alternative names
fluconazole
Therapeutic class
Triazole Antifungal
Pharmacological class
Antifungal Agent
Contraindications
concurrent use of QT-prolonging drugs; hypersensitivity to azole antifungals
Minor side effects
nausea; headache; abdominal pain
Moderate side effects
elevated liver transaminases; diarrhoea; rash
Dosage forms
Tablet
Administration route
Oral use
Originator
Pfizer
Onset time
24–48 hours
Duration
2–4 days
Storage instructions
Store below 25°C.
Drug interactions
Warfarin; Pimozide; Simvastatin
Age restrictions
Approved for paediatric and adult populations.
Serious side effects

Stevens-Johnson syndrome, requires immediate medical attention; severe hepatotoxicity, requires immediate medical attention

Patient summary

Fluconazole tablets for yeast infections, including vaginal thrush. It prevents the fungus from building its cell wall.

Mechanism of action

Inhibits the enzyme lanosterol 14-alpha-demethylase, preventing vital ergosterol synthesis required for fungal cell walls.

Pregnancy and breastfeeding

Pregnancy: High dose linked to congenital defects. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.

FAQ

Will I receive the original Diflucan?

No. Diflucan is the original brand, made by Pfizer, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (fluconazole) at the strength you choose. The generic brand and manufacturer depend on available stock.

How much does Diflucan cost in South Africa?

Diflucan comes in 50mg, 100mg, 150mg, 200mg and 400mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

Is Diflucan sold under other names?

In South Africa, fluconazole is also sold under brand names such as Rucintix, Difluzole and Mycorest.

What is Diflucan used for?

Diflucan contains fluconazole, used for vulvovaginal candidiasis, systemic candidiasis and cryptococcal meningitis.

When does Diflucan start working?

Fluconazole usually starts to work within 24 to 48 hours. This varies from person to person.

What are the side effects of Diflucan?

The common side effects of fluconazole are nausea, headache and abdominal pain. Less common ones include elevated liver transaminases, diarrhoea and rash. Serious but less common side effects include Stevens-Johnson syndrome and severe liver damage (hepatotoxicity), which need urgent medical attention.

Which medicines interact with Diflucan?

Fluconazole can interact with warfarin, pimozide and simvastatin. Tell your doctor or pharmacist about every medicine you take before you start taking Diflucan.

Is Diflucan available over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Diflucan. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Diflucan in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Diflucan names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Fluconazole at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics