Hyzaar
Losartan · Hydrochlorothiazide
Losartan and hydrochlorothiazide tablets for high blood pressure and stroke prevention. Losartan blocks a constricting hormone, the diuretic removes extra fluid.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 12.5mg + 12.5mg | 30 tablets | $33.00 | $1.10 |
| 12.5mg + 12.5mg | 60 tablets | $54.00 | $0.90 |
| 12.5mg + 12.5mg | 90 tablets | $81.00 | $0.90 |
| 12.5mg + 12.5mg | 120 tablets | $97.00 | $0.81 |
| 12.5mg + 12.5mg | 180 tablets | $135.00 | $0.75 |
| 12.5mg + 12.5mg | 360 tablets | $227.00 | $0.63 |
| 25mg + 12.5mg | 30 tablets | $20.00 | $0.67 |
| 25mg + 12.5mg | 60 tablets | $36.00 | $0.60 |
| 25mg + 12.5mg | 90 tablets | $48.00 | $0.53 |
| 25mg + 12.5mg | 120 tablets | $61.00 | $0.51 |
| 50mg + 12.5mg | 30 tablets | $71.00 | $2.37 |
| 50mg + 12.5mg | 60 tablets | $121.00 | $2.02 |
| 50mg + 12.5mg | 90 tablets | $171.00 | $1.90 |
| 50mg + 12.5mg | 120 tablets | $221.00 | $1.84 |
| 50mg + 12.5mg | 180 tablets | $323.00 | $1.79 |
| 50mg + 12.5mg | 270 tablets | $475.00 | $1.76 |
| 50mg + 12.5mg | 360 tablets | $628.00 | $1.74 |
- Category
- Heart & Blood Pressure
- Active ingredients
- Losartan · Hydrochlorothiazide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 12.5mg + 12.5mg · 25mg + 12.5mg · 50mg + 12.5mg
Hyzaar is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Hyzaar on your behalf.
- Conditions
- Hypertension · Stroke Prevention
- Alternative names
- losartan, hydrochlorothiazide
- Therapeutic class
- Angiotensin II Receptor Antagonist, Thiazide Diuretic Combination
- Pharmacological class
- Antihypertensive Combination
- Contraindications
- pregnancy; anuria; severe renal impairment
- Minor side effects
- dizziness; headache; fatigue
- Moderate side effects
- hyperkalaemia; electrolyte depletion; hypotension
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Merck
- Onset time
- 1–2 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Lithium; NSAIDs; Potassium Supplements
- Age restrictions
- Approved for adults.
Serious side effects
angioedema, requires immediate medical attention; severe acute renal failure, requires immediate medical attention
Patient summary
Losartan and hydrochlorothiazide tablets for high blood pressure and stroke prevention. Losartan blocks a constricting hormone, the diuretic removes extra fluid.
Mechanism of action
Losartan blocks vasoconstricting AT1 receptors, while hydrochlorothiazide clears excess sodium and water via the kidneys.
Pregnancy and breastfeeding
Pregnancy: High risk of fetal injury and death. Contraindicated in pregnancy. Breastfeeding: Not recommended.
FAQ
Will I receive the original Hyzaar?
No. Hyzaar is the original brand, made by Merck, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredients (losartan and hydrochlorothiazide) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Hyzaar cost in South Africa?
Hyzaar comes in 12.5mg + 12.5mg, 25mg + 12.5mg and 50mg + 12.5mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →Is Hyzaar sold under other names?
In South Africa, losartan and hydrochlorothiazide are also sold under brand names such as Losaar, Zartan Co and Co-Normoten.
What is Hyzaar used for?
Hyzaar contains losartan and hydrochlorothiazide, used for hypertension and stroke prevention.
How long does Hyzaar take to work?
Losartan and hydrochlorothiazide usually start to work within 1 to 2 hours, and their effect lasts about 24 hours. How quickly they work can differ from one person to another.
Does Hyzaar have side effects?
Yes. The common side effects of losartan and hydrochlorothiazide are dizziness, headache and fatigue. Less common ones include hyperkalaemia, electrolyte depletion and hypotension. Serious but less common side effects include angioedema and severe acute renal failure, which need urgent medical attention.
What does Hyzaar interact with?
Losartan and hydrochlorothiazide can interact with lithium, NSAIDs and potassium supplements. Tell your doctor or pharmacist about every medicine you take before you start taking Hyzaar.
Do I need a prescription to buy Hyzaar in South Africa?
No, not online: Direct Meds does not ask for a prescription to order Hyzaar. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver Hyzaar to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Hyzaar names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Losartan / Hydrochlorothiazide at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.