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Motilium

Motilium

Domperidone

Domperidone tablets for nausea and vomiting. They speed up stomach emptying, which also reduces a heavy feeling after meals.

All strengths and pack prices
StrengthPackPricePer unit
10mg10 tablets$63.00$6.30
10mg20 tablets$70.00$3.50
10mg30 tablets$77.00$2.57
10mg60 tablets$86.00$1.43
10mg90 tablets$94.00$1.04
10mg120 tablets$101.00$0.84
10mg180 tablets$109.00$0.61
10mg270 tablets$132.00$0.49
10mg360 tablets$147.00$0.41
Active ingredient
Domperidone
Route
Oral use
Form
Tablet
Strengths
10mg

Motilium is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Motilium on your behalf.

Alternative names
domperidone
Therapeutic class
Dopamine Antagonist
Pharmacological class
Prokinetic and Antiemetic
Known off-label uses
lactation induction
Contraindications
prolonged QT interval; gastrointestinal haemorrhage; prolactinoma
Minor side effects
dry mouth; headache; nausea
Moderate side effects
amenorrhoea; gynaecomastia; abdominal cramps
Dosage forms
Tablet
Administration route
Oral use
Originator
Janssen
Onset time
30–60 minutes
Duration
6–8 hours
Storage instructions
Store below 25°C.
Drug interactions
Ketoconazole; Erythromycin; QT-prolonging drugs
Age restrictions
Approved for adults.
Serious side effects

QT prolongation, requires immediate medical attention; torsades de pointes, requires immediate medical attention

Patient summary

Domperidone tablets for nausea and vomiting. They speed up stomach emptying, which also reduces a heavy feeling after meals.

Mechanism of action

Selectively blocks peripheral dopamine receptors, increasing lower oesophageal pressure and accelerating gastric emptying.

Pregnancy and breastfeeding

Pregnancy: Safety has not been systematically established. Breastfeeding: Expelled in low quantities.

FAQ

Is the Motilium on Direct Meds a generic?

Yes, you receive a generic. Motilium is the original brand, made by Janssen, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (domperidone) at the same strength. The generic brand and manufacturer depend on available stock.

How much does Motilium cost in South Africa?

Motilium comes in a 10mg strength, in packs of 10 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

What are the brand names for domperidone in South Africa?

In South Africa, domperidone is also sold under brand names such as Vomidon and Vomi-Guard.

What is Motilium used for?

Motilium contains domperidone, used for nausea and vomiting and indigestion (dyspepsia).

How long does Motilium take to work?

Domperidone usually starts to work within 30 to 60 minutes, and its effect lasts about 6 to 8 hours. This varies from person to person.

What are the side effects of Motilium?

The common side effects of domperidone are dry mouth, headache and nausea. Less common ones include amenorrhoea, gynaecomastia and abdominal cramps. Serious but less common side effects include QT prolongation and torsades de pointes, which need urgent medical attention.

Which medicines interact with Motilium?

Domperidone can interact with ketoconazole, erythromycin and QT-prolonging drugs. Tell your doctor or pharmacist about every medicine you take before you start taking Motilium.

Is Motilium available over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Motilium. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Can I buy Motilium online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Motilium names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Domperidone at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics