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Pristiq

Pristiq

Desvenlafaxine

Desvenlafaxine tablets for major depressive disorder. It raises both serotonin and norepinephrine, making it different from SSRIs that target one.

All strengths and pack prices
StrengthPackPricePer unit
50mg100 tablets$130.00$1.30
50mg200 tablets$235.00$1.18
50mg300 tablets$344.00$1.15
50mg400 tablets$426.00$1.07
100mg30 tablets$110.00$3.67
100mg40 tablets$140.00$3.50
100mg60 tablets$203.00$3.38
100mg90 tablets$293.00$3.26
100mg120 tablets$386.00$3.22
100mg180 tablets$571.00$3.17
100mg270 tablets$849.00$3.14
Active ingredient
Desvenlafaxine
Route
Oral use
Form
Tablet
Strengths
50mg · 100mg

Pristiq is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Pristiq on your behalf.

Alternative names
desvenlafaxine
Therapeutic class
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Pharmacological class
Antidepressant
Known off-label uses
vasomotor menopausal symptoms
Contraindications
concurrent MAO inhibitor use
Minor side effects
nausea; dry mouth; somnolence
Moderate side effects
insomnia; sweating; sexual dysfunction
Dosage forms
Tablet
Administration route
Oral use
Originator
Pfizer
Onset time
1–4 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
MAO Inhibitors; Aspirin; NSAIDs
Age restrictions
Approved for adults over eighteen years.
Serious side effects

suicidal ideation, requires immediate medical attention; serotonin syndrome, requires immediate medical attention

Patient summary

Desvenlafaxine tablets for major depressive disorder. It raises both serotonin and norepinephrine, making it different from SSRIs that target one.

Mechanism of action

Potently inhibits presynaptic serotonin and norepinephrine reuptake, boosting active transmitter pools in target synapses.

Pregnancy and breastfeeding

Pregnancy: Use if benefit outweighs risk. Monitor newborn. Breastfeeding: Consult a doctor.

FAQ

Will I receive the original Pristiq?

No. Pristiq is the original brand, made by Pfizer, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (desvenlafaxine) at the strength you choose. The generic brand and manufacturer depend on available stock.

How is Pristiq priced?

It depends on the strength and pack. Pristiq comes in 50mg and 100mg strengths, in packs of 30 to 400 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

Is Pristiq sold under other names?

In South Africa, desvenlafaxine is also sold under brand names such as Exlov, Exsira and Depven.

What is Pristiq used for?

Pristiq contains desvenlafaxine, used for major depressive disorder.

How quickly does Pristiq work?

Desvenlafaxine usually starts to work within 1 to 4 weeks. How quickly it works can differ from one person to another.

What are the side effects of Pristiq?

The common side effects of desvenlafaxine are nausea, dry mouth and drowsiness (somnolence). Less common ones include insomnia, sweating and sexual dysfunction. Serious but less common side effects include suicidal ideation and serotonin syndrome, which need urgent medical attention.

Which medicines interact with Pristiq?

Desvenlafaxine can interact with MAO inhibitors, aspirin and NSAIDs. Tell your doctor or pharmacist about every medicine you take before you start taking Pristiq.

Can I buy Pristiq over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Pristiq. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Do you deliver Pristiq to South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Pristiq names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Desvenlafaxine at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics