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Zoloft

Zoloft

Sertraline

Sertraline tablets for major depressive disorder and panic disorder. It is an SSRI that can take a few weeks to show its full effect.

All strengths and pack prices
StrengthPackPricePer unit
25mg90 tablets$42.00$0.47
25mg120 tablets$50.00$0.42
25mg180 tablets$66.00$0.37
25mg270 tablets$90.00$0.33
25mg360 tablets$114.00$0.32
50mg60 tablets$75.00$1.25
50mg90 tablets$87.00$0.97
50mg120 tablets$101.00$0.84
50mg180 tablets$125.00$0.69
50mg270 tablets$163.00$0.60
50mg360 tablets$201.00$0.56
100mg30 tablets$70.00$2.33
100mg60 tablets$94.00$1.57
100mg90 tablets$118.00$1.31
100mg120 tablets$146.00$1.22
100mg180 tablets$193.00$1.07
100mg270 tablets$264.00$0.98
100mg360 tablets$340.00$0.94
Active ingredient
Sertraline
Route
Oral use
Form
Tablet
Strengths
25mg · 50mg · 100mg

Zoloft is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Zoloft on your behalf.

Alternative names
sertraline
Therapeutic class
Selective Serotonin Reuptake Inhibitor (SSRI)
Pharmacological class
SSRI
Known off-label uses
premature ejaculation
Contraindications
concurrent use of MAO inhibitors; pimozide use
Minor side effects
nausea; dry mouth; somnolence
Moderate side effects
insomnia; anorexia; sexual dysfunction
Dosage forms
Tablet
Administration route
Oral use
Originator
Pfizer
Onset time
2–4 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
MAO Inhibitors; Pimozide; Aspirin; NSAIDs
Age restrictions
Approved for children over six years (for OCD) and adults.
Serious side effects

suicidal ideation, requires immediate medical attention; serotonin syndrome, requires immediate medical attention

Patient summary

Sertraline tablets for major depressive disorder and panic disorder. It is an SSRI that can take a few weeks to show its full effect.

Mechanism of action

Selectively blocks presynaptic serotonin reuptake, sustaining neurotransmitter availability within critical mood-regulating synapses.

Pregnancy and breastfeeding

Pregnancy: Use if potential benefits justify risks. Monitor newborn. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.

FAQ

Is the Zoloft sold here the original brand?

No. Zoloft is the original brand, made by Pfizer, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (sertraline) at the strength you choose. The generic brand and manufacturer depend on available stock.

How much does Zoloft cost in South Africa?

Zoloft comes in 25mg, 50mg and 100mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.

Payment and prices →

Is Zoloft sold under other names?

In South Africa, sertraline is also sold under brand names such as Serdep and Serlife.

When does Zoloft start working?

Sertraline usually starts to work within 2 to 4 weeks. How quickly it works can differ from one person to another.

What side effects can Zoloft cause?

The common side effects of sertraline are nausea, dry mouth and drowsiness (somnolence). Less common ones include insomnia, loss of appetite and sexual dysfunction. Serious but less common side effects include suicidal ideation and serotonin syndrome, which need urgent medical attention.

Which medicines interact with Zoloft?

Sertraline can interact with MAO inhibitors, pimozide, aspirin and NSAIDs. Tell your doctor or pharmacist about every medicine you take before you start taking Zoloft.

Do I need a prescription to buy Zoloft in South Africa?

No, not online: Direct Meds does not ask for a prescription to order Zoloft. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Do you deliver Zoloft to South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Zoloft names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Sertraline at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics