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Accutane

Accutane

Isotretinoin

Isotretinoin capsules for severe acne. The skin becomes much more sensitive to sunlight during treatment.

All strengths and pack prices
StrengthPackPricePer unit
5mg10 capsules$33.00$3.30
5mg20 capsules$37.00$1.85
5mg30 capsules$41.00$1.37
5mg60 capsules$61.00$1.02
5mg90 capsules$81.00$0.90
5mg120 capsules$96.00$0.80
5mg180 capsules$113.00$0.63
5mg270 capsules$145.00$0.54
5mg360 capsules$161.00$0.45
10mg10 capsules$37.00$3.70
10mg20 capsules$45.00$2.25
10mg30 capsules$49.00$1.63
10mg60 capsules$73.00$1.22
10mg90 capsules$97.00$1.08
10mg120 capsules$113.00$0.94
10mg180 capsules$145.00$0.81
10mg270 capsules$200.00$0.74
10mg360 capsules$236.00$0.66
20mg10 capsules$40.00$4.00
20mg20 capsules$49.00$2.45
20mg30 capsules$57.00$1.90
20mg60 capsules$113.00$1.88
20mg90 capsules$145.00$1.61
20mg120 capsules$169.00$1.41
20mg180 capsules$217.00$1.21
20mg270 capsules$305.00$1.13
20mg360 capsules$377.00$1.05
30mg10 capsules$49.00$4.90
30mg20 capsules$57.00$2.85
30mg30 capsules$73.00$2.43
30mg60 capsules$145.00$2.42
30mg90 capsules$192.00$2.13
30mg120 capsules$240.00$2.00
30mg180 capsules$320.00$1.78
30mg270 capsules$400.00$1.48
30mg360 capsules$479.00$1.33
40mg10 capsules$56.00$5.60
40mg20 capsules$65.00$3.25
40mg30 capsules$95.00$3.17
40mg60 capsules$174.00$2.90
40mg90 capsules$237.00$2.63
40mg120 capsules$308.00$2.57
40mg180 capsules$394.00$2.19
40mg270 capsules$473.00$1.75
40mg360 capsules$512.00$1.42
Category
Skin Care
Active ingredient
Isotretinoin
Route
Oral use
Form
Capsule
Strengths
5mg · 10mg · 20mg · 30mg · 40mg

Accutane is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Accutane on your behalf.

Alternative names
isotretinoin
Therapeutic class
Retinoid
Pharmacological class
Systemic Retinoid
Known off-label uses
rosacea; discoid lupus erythematosus
Contraindications
pregnancy; hypersensitivity to isotretinoin; hepatic impairment
Minor side effects
dry skin; dry eyes; chapped lips
Moderate side effects
elevated triglycerides; elevated liver enzymes; musculoskeletal pain
Dosage forms
Capsule
Administration route
Oral use
Originator
Roche
Onset time
2–4 weeks
Duration
12–24 hours
Storage instructions
Store below 25°C.
Drug interactions
Tetracycline; Vitamin A; Alcohol
Age restrictions
Approved for adults and adolescents.
Serious side effects

suicidal ideation, requires immediate medical attention; severe hepatotoxicity, requires immediate medical attention

Patient summary

Isotretinoin capsules for severe acne. The skin becomes much more sensitive to sunlight during treatment.

Mechanism of action

Suppresses sebaceous gland activity, dramatically decreasing sebum secretion, which inhibits inflammatory lesion formation on the skin.

Pregnancy and breastfeeding

Pregnancy: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.

FAQ

Is the Accutane on Direct Meds a generic?

Yes, you receive a generic. Accutane is the original brand, made by Roche, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (isotretinoin) at the strength you choose. The generic brand and manufacturer depend on available stock.

How is Accutane priced?

It depends on the strength and pack. Accutane comes in 5mg, 10mg, 20mg, 30mg and 40mg strengths, in packs of 10 to 360 capsules, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per capsule.

Payment and prices →

What other names is Accutane sold under?

In South Africa, isotretinoin is also sold under brand names such as Oratane, Acnetane and Supatane. On Direct Meds the same ingredient is also sold as Accufine and Isotroin.

What is Accutane used for?

Accutane contains isotretinoin, used for severe recalcitrant nodular acne.

When does Accutane start working?

Isotretinoin usually starts to work within 2 to 4 weeks. The exact timing differs between people.

What side effects can Accutane cause?

The common side effects of isotretinoin are dry skin, dry eyes and chapped lips. Less common ones include elevated triglycerides, elevated liver enzymes and musculoskeletal pain. Serious but less common side effects include suicidal ideation and severe liver damage (hepatotoxicity), which need urgent medical attention.

Can I drink alcohol with Accutane?

Alcohol can interact with isotretinoin, so check with a doctor or pharmacist before you drink while taking Accutane.

What does Accutane interact with?

Isotretinoin can interact with tetracycline and vitamin A. Tell your doctor or pharmacist about every medicine you take before you start taking Accutane.

Is Accutane available over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Accutane. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Accutane in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Accutane names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Isotretinoin at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics