Prograf
Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.
- Category
- Autoimmune Support
- Active ingredient
- Tacrolimus
- Route
- Oral use
- Form
- Tablet
- Strengths
- 0.5mg · 1mg · 5mg
Prograf is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Prograf depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Prograf details
- Condition
- Organ Transplant Rejection
- Alternative names
- tacrolimus
- Therapeutic class
- Calcineurin Inhibitor
- Pharmacological class
- Immunosuppressant
- Known off-label uses
- severe active rheumatoid arthritis
- Contraindications
- hypersensitivity to tacrolimus
- Minor side effects
- headache; tremor; nausea
- Moderate side effects
- renal dysfunction; hypertension; hyperglycaemia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Astellas Pharma
- Onset Time
- 2–4 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Ketoconazole; Rifampin; Grapefruit
- Age restrictions
- Approved for children and adults under specialist care.
Serious side effects
severe nephrotoxicity, requires immediate medical attention; severe systemic infections, requires immediate medical attention
Patient summary
Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.
Mechanism of action
Binds to intracellular immunophilins to block calcineurin, stopping critical T-cell transcription processes.
Pregnancy and breastfeeding
Pregnancy: Use if potential benefits justify risks. Breastfeeding: Contraindicated.
What you will receive
Prograf names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Tacrolimus at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.