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Organ Transplant Rejection

Organ transplant rejection happens when the recipient’s immune system recognises the new organ as foreign and attacks it. Without immune suppression, the body will nearly always mount a destructive response against the transplanted tissue.

Imuran

Azathioprine

25mg · 50mg

Azathioprine tablets for rheumatoid arthritis and to prevent organ transplant rejection. It blocks the growth of white blood cells.

From$1.55/ tabletView

Cellcept

Mycophenolate Mofetil

250mg · 500mg

Mycophenolate mofetil capsules for preventing organ transplant rejection. It targets lymphocytes specifically, reducing the risk of the body attacking the new organ.

From$2.91/ capsuleView

Prograf

Tacrolimus

0.5mg · 1mg · 5mg

Tacrolimus tablets to stop organ transplant rejection. It suppresses the immune system's attack on the new organ and requires regular blood level checks.

From$3.34/ tabletView

Ciclosporin Capsules

Ciclosporin

50mg · 100mg

Ciclosporin capsules for rheumatoid arthritis and psoriasis. It suppresses T-lymphocyte activity by blocking a specific cell-signalling pathway.

From$4.10/ capsuleView

Key points

  • Every transplant recipient experiences some degree of acute rejection, making it a near-universal event after organ transplantation.
  • Symptoms vary by organ; kidney rejection may reduce urine output while heart rejection may produce heart-failure symptoms.
  • A biopsy of the transplanted organ is used to confirm rejection and assess its severity.

Medicines listed for Organ Transplant Rejection

The listed products contain azathioprine, mycophenolate mofetil, tacrolimus and ciclosporin. Each belongs to the immunosuppressant class, which dampens the immune system’s response so the transplanted organ can continue to function. Azathioprine is supplied as a tablet, while Mycophenolate Mofetil comes as a capsule. Tacrolimus is a tablet and ciclosporin a capsule.

Further reading