Rybelsus
Semaglutide tablets for type 2 diabetes. It mimics a gut hormone to release more insulin and slow stomach emptying.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 3mg | 10 tablets | $200.00 | $20.00 |
| 3mg | 20 tablets | $337.00 | $16.85 |
| 3mg | 30 tablets | $440.00 | $14.67 |
| 7mg | 10 tablets | $265.00 | $26.50 |
| 7mg | 20 tablets | $449.00 | $22.45 |
| 7mg | 30 tablets | $641.00 | $21.37 |
| 14mg | 10 tablets | $289.00 | $28.90 |
| 14mg | 20 tablets | $497.00 | $24.85 |
| 14mg | 30 tablets | $705.00 | $23.50 |
- Categories
- Diabetes Management · Weight Management
- Active ingredient
- Semaglutide
- Route
- Oral use
- Form
- Tablet
- Strengths
- 3mg · 7mg · 14mg
Rybelsus is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Rybelsus on your behalf.
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- semaglutide
- Therapeutic class
- Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist
- Pharmacological class
- GLP-1 Receptor Agonist
- Known off-label uses
- chronic weight management
- Minor side effects
- nausea; vomiting; diarrhoea
- Moderate side effects
- abdominal pain; decreased appetite; constipation
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Novo Nordisk
- Onset time
- 2–4 weeks
- Duration
- 24 hours to 7 days
- Storage instructions
- Store below 25°C. Keep in original blister pack.
- Drug interactions
- Insulin; Sulfonylureas; Oral Medications requiring rapid absorption
- Age restrictions
- Approved for adults.
Contraindications
history of medullary thyroid carcinoma; multiple endocrine neoplasia syndrome type 2; diabetic ketoacidosis
Serious side effects
acute pancreatitis, requires immediate medical attention; anaphylaxis, requires immediate medical attention; acute kidney injury, requires immediate medical attention
Patient summary
Semaglutide tablets for type 2 diabetes. It mimics a gut hormone to release more insulin and slow stomach emptying.
Mechanism of action
Stimulates the GLP-1 receptor, boosting glucose-dependent insulin release while slowing stomach emptying and decreasing appetite.
Pregnancy and breastfeeding
Pregnancy: Discontinue at least two months prior to a planned pregnancy. Breastfeeding: Avoid.
FAQ
Is the Rybelsus on Direct Meds a generic?
Yes, you receive a generic. Rybelsus is the original brand, made by Novo Nordisk, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (semaglutide) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Rybelsus cost in South Africa?
It depends on the strength and pack. Rybelsus comes in 3mg, 7mg and 14mg strengths, in packs of 10 to 30 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What is Rybelsus used for?
Rybelsus contains semaglutide, used for type 2 diabetes mellitus.
How quickly does Rybelsus work?
Semaglutide usually starts to work within 2 to 4 weeks. The exact timing differs between people.
What are the side effects of Rybelsus?
The common side effects of semaglutide are nausea, vomiting and diarrhoea. Less common ones include abdominal pain, decreased appetite and constipation. Serious but less common side effects include acute pancreatitis, anaphylaxis and acute kidney injury, which need urgent medical attention.
What does Rybelsus interact with?
Semaglutide can interact with insulin, sulfonylureas and oral medications requiring rapid absorption. Tell your doctor or pharmacist about every medicine you take before you start taking Rybelsus.
Can I buy Rybelsus over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Rybelsus. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Rybelsus online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Rybelsus names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Semaglutide at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.