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Keftab (Cephalexin) Buyer and Patient Handbook in South Africa

What is Keftab?

Keftab is a Cephalexin tablet belonging to the first-generation cephalosporin antibiotics class. It is used to treat bacterial infections such as skin-soft tissue infections, urinary-tract infections, and respiratory tract infections. The product is authorised by the South African Health Products Regulatory Authority (SAHPRA) and is available in tablet form.

Who Should Use Keftab?

• Adults with uncomplicated bacterial infections
• Adolescents (12 years and older) where dosing is appropriate
• Patients needing a short-course oral antibiotic for outpatient care

How Does It Work?

Cephalexin blocks bacterial cell-wall synthesis, leading to rupture of the microbe and elimination of the infection. Think of it as stopping a construction crew from finishing a building; the bacteria cannot complete their protective wall and collapse. It has low potential for abuse, but resistance can develop if used improperly.

Why Choose Keftab?

• Generic advantage: offers the same clinical benefit as brand-name cephalexin at a lower cost.
• Quality assurance: manufactured under Good Manufacturing Practice (GMP) standards.
• Off-label uses exist (e.g., prophylaxis before certain dental procedures) but should only be considered after professional guidance.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 125 mg - 250 mg - 375 mg - 500 mg - 750 mg tablets, taken as directed by your healthcare professional.

How to Take

• Swallow the tablet whole with a full glass of water.
• Can be taken with or without food; food may reduce stomach upset.

Missed Dose

• Take the missed dose as soon as you remember, unless it is almost time for the next dose.
• Do not double-dose.

Overdose

• Seek immediate medical attention.
• Symptoms may include nausea, vomiting, diarrhoea, and dizziness.

Special Populations

• Elderly: monitor kidney function; dose may need adjustment.
• Children: not recommended below 12 years unless prescribed by a clinician.
• Renal impairment: reduce dose according to renal clearance.

Lifestyle & Diet

• Avoid taking Keftab with large amounts of calcium-rich antacids at the same time; separate by at least 2 hours.
• No restriction on alcohol, but limit excessive intake as it may worsen side-effects.

Precautions and Warnings

• Use only for bacterial infections confirmed or strongly suspected; viral infections will not improve.
• Discontinue if you develop a rash, itching, swelling, or difficulty breathing.
• Inform your healthcare provider of any history of Allergic Reactions to penicillins or other cephalosporins.

Drug Interactions

Potential Side Effects

Common Side Effects

• Nausea
• Diarrhoea
• Mild skin rash

Less Common Side Effects

• Abdominal Pain
• Headache
• Vomiting

Serious Side Effects

• Severe allergic reaction (Anaphylaxis) - seek emergency care
• Clostridioides difficile-associated colitis - contact a clinician if severe diarrhoea occurs
• Liver enzyme elevation - monitor if symptoms of hepatitis appear

Who Should Avoid This Medication?

• Known allergy to cephalexin or other cephalosporins
• History of severe penicillin allergy (cross-reactivity risk)
• End-stage renal disease without dose adjustment

Storage Instructions

• Store at 15-30 °C, protected from moisture and light.
• Keep out of reach of children.
• Do not use tablets after the expiry date printed on the pack.

Keftab Alternatives

Frequently Asked Questions

How long does a typical course of Keftab last?

A standard adult course is usually 7-10 days, but exact duration depends on the infection type and clinical response.

Can I take Keftab with food?

Yes, it may be taken with or without meals; food can help minimise stomach upset.

Will Keftab affect my birth control pill?

It can reduce the effectiveness of hormonal contraception; use a barrier method or another backup method while on Keftab.

Is it safe to take Keftab while pregnant?

Cephalexin is generally considered safe in pregnancy (Category B), but discuss any use with your obstetric provider.

What should I do if I develop a rash?

Stop the medication immediately and seek medical attention; a rash can signal an allergic reaction.

Can I drink alcohol while on Keftab?

Moderate alcohol intake is not contraindicated, but excessive drinking may worsen side-effects like dizziness.

How quickly will I feel better after starting Keftab?

Symptoms often improve within 48-72 hours; if there is no improvement, contact a healthcare professional.

Do I need to complete the whole course even if I feel better?

Yes, finishing the prescribed course prevents infection recurrence and reduces resistance risk.

Glossary

• Cephalosporin: A class of antibiotics that disrupt bacterial cell-wall synthesis.
• Renal clearance: The kidney’s ability to remove a drug from the bloodstream.
• Cross-reactivity: An allergic response to similar drug structures, such as between penicillins and cephalosporins.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses are mentioned solely for awareness; any such use should be discussed with a qualified healthcare provider. Keftab is supplied through our online pharmacy platform; we do not dispense prescriptions. Users are responsible for ensuring the medication is appropriate for their condition and for following all safety instructions. Always consult a qualified health professional before starting or stopping any medication.