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Aropax (Paroxetine) Buyer and Patient Handbook in South Africa

What is Aropax?

Aropax is a selective serotonin reuptake inhibitor (SSRI) used to treat Major Depressive Disorder, Anxiety disorders, obsessive-compulsive disorder, and related conditions. It belongs to the antidepressant class and is approved by the South African Health Products Regulatory Authority (SAHPRA) and the FDA. Aropax is supplied as a tablet (pill) in strengths of 10 mg, 20 mg, 30 mg, and 40 mg.

Who Should Use Aropax?

• Adults diagnosed with major depressive disorder.
• Patients with Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, or obsessive-compulsive disorder.
• Individuals for whom other antidepressants have been ineffective or poorly tolerated.

How Does It Work?

Aropax blocks the reabsorption (reuptake) of serotonin in the brain, increasing its availability at nerve synapses. More serotonin improves mood, reduces anxiety, and stabilises mood swings. The medication has a low potential for abuse, but sudden discontinuation can cause withdrawal-like symptoms.

Why Choose Aropax?

• Generic advantage: Cost-effective while meeting the same quality standards as brand-name paroxetine.
• Proven efficacy: Multiple clinical trials support its use for Depression and anxiety.
• Flexible dosing: Available in four strengths to allow precise titration. (Off-label uses should be discussed with a healthcare professional.)

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Start with 10 mg once daily, typically in the morning.
• Increase to 20 mg after 1 week if needed; maximum 40 mg once daily.

How to Take

• Swallow the tablet whole with a full glass of water.
• Can be taken with or without food; consistency each day helps maintain stable blood levels.

Missed Dose

• If you remember within 12 hours, take the missed dose.
• If it’s later than 12 hours, skip it and continue with the next scheduled dose.

Overdose

• Call emergency services (112) immediately.
• Provide details of the amount taken and time of ingestion.

Special Populations

• Elderly: Start at 10 mg; monitor for increased sensitivity to side effects.
• Renal/hepatic impairment: May require dose reduction; consult a healthcare professional.
• Pregnancy & breastfeeding: Discuss risks and benefits; use only if clearly needed.

Lifestyle & Diet

• Avoid alcohol as it may intensify Drowsiness.
• Grapefruit juice can increase paroxetine levels; limit intake.
• Maintain regular sleep patterns; abrupt changes can worsen side effects.

Precautions and Warnings

• Do not combine with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI.
• Monitor for worsening depression or emergence of suicidal thoughts, especially during the first few weeks.
• Caution in patients with a history of Bipolar Disorder, seizure disorders, or bleeding disorders.

Drug Interactions

Potential Side Effects

Common Side Effects

• Nausea, dry mouth, headache, dizziness, Insomnia, or somnolence.

Less Common Side Effects

• Sexual dysfunction, constipation, increased sweating, tremor, weight change.

Serious Side Effects

• Signs of serotonin syndrome (fever, Agitation, rapid heartbeat).
• Severe allergic reaction (rash, swelling, difficulty breathing).
• Unusual bleeding or bruising. Seek immediate medical help if any occur.

Who Should Avoid This Medication?

• Individuals allergic to paroxetine or any tablet ingredients.
• Patients currently on MAO inhibitors or who stopped an MAOI less than 14 days ago.
• Those with uncontrolled narrow-angle Glaucoma.

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at 15-30 °C (59-86 °F), away from moisture and direct light.
• Keep out of reach of children and pets.

Aropax Alternatives

Frequently Asked Questions

How long does it take to feel the effect of Aropax?

Most patients notice an improvement in mood within 2-4 weeks, but full benefits may require up to 8 weeks.

Can I drink coffee while taking Aropax?

Yes, moderate coffee consumption is safe, but excessive caffeine can increase anxiety or insomnia.

Is it safe to drive or operate machinery?

Aropax may cause dizziness or drowsiness initially; avoid driving until you know how it affects you.

What should I do if I experience sexual side effects?

Discuss the issue with a healthcare professional; dose adjustment or a switch to another antidepressant may help.

Can I take Aropax with my blood pressure medication?

Most blood pressure drugs have no major interaction, but always confirm with a healthcare professional.

Why did I gain weight after starting Aropax?

Weight changes are a known side effect of SSRIs; maintain a balanced diet and regular exercise.

Is it necessary to take the tablet at the same time every day?

Taking Aropax at the same time each day helps maintain steady blood levels and reduces side-effect risk.

What happens if I stop Aropax abruptly?

Sudden discontinuation can cause withdrawal symptoms such as flu-like feelings, irritability, or electric-shock sensations; tapering under professional guidance is recommended.

Glossary

• Serotonin reuptake inhibitor: A drug that blocks the reabsorption of serotonin, increasing its amount in the brain.
• Serotonin syndrome: A potentially life-threatening condition caused by excess serotonin, marked by agitation, fever, and rapid heart rate.
• Titration: Gradually adjusting the dose to find the most effective and tolerable amount.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses should be discussed with a qualified healthcare professional. Readers are responsible for verifying the suitability of any medication for their personal health circumstances. Our platform offers convenient access to medicines, but all decisions regarding use should be made in consultation with a qualified health provider.